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Signaling pathways involved in liver injury and regeneration in rabbit hemorr...

García-Lastra(Rodrigo),San-Miguel(Beatriz)... Vet Res 2010-03-30

...SOCS3 expression increased significantly. The current findings suggest that activation of JNK is an essential component ...

Leptin receptor 170 kDa (OB-R170) protein expression is reduced in obese huma...

Fuentes(T),Ara(I),Guadalupe-Grau(A),Larsen... Exp Physiol 2010-08-04

...SOCS3) and protein tyrosine phosphatase 1B (PTP1B) in skeletal muscle, which blunt janus kinase 2-dependent leptin signa...

Knocking off the suppressors of cytokine signaling (SOCS): their roles in mam...

Fitzgerald(Justine S),Toth(Bettina),Jeschk... J Reprod Immunol 2010-06-08

...SOCS3 is embryonically lethal due to placental insufficiency, while SOCS3 over-expression leads to elevated Th2 response...

Impairment of gamma interferon signaling in human neutrophils infected with A...

Bussmeyer(Uta),Sarkar(Arup),Broszat(Kirste... Infect Immun 2010-01-21

...SOCS3 in PMN. Since IFN-gamma activates various antibacterial effector mechanisms of PMN, the impaired IFN-gamma signali...

Antigen presentation by dendritic cells in tumors is disrupted by altered met...

Zhang(Zhuohan),Liu(Qiaofei),Che(Yongzhe),Y... Cancer Res 2010-01-26

...SOCS3 with M2-PK reduced ATP production and impaired DC-based immunotherapy against tumors. Thus, SOCS3, which has been ...

Hepatitis B virus overexpresses suppressor of cytokine signaling-3 (SOCS3) th...

Koeberlein(Bernd),zur Hausen(Axel),Bektas(... Virus Res 2010-04-26

...SOCS3 protein. In spite of the over expression of its negative regulator SOCS3 we observed a constitutive activation of ...

Taking off the SOCS: cytokine signaling spurs regeneration.

Newbern(Jason M),Shoemaker(Sarah E),Snider... Neuron 2010-01-05

...SOCS3 acts as a key negative regulator of adult optic nerve regeneration.

SOCS3 deletion promotes optic nerve regeneration in vivo.

Smith(Patrice D),Sun(Fang),Park(Kevin Kyun... Neuron 2010-01-05

...SOCS3-gp130 double-knockout mice, suggesting that SOCS3 deletion promotes axon regeneration via a gp130-dependent pathwa...

CD14 signaling restrains chronic inflammation through induction of p38-MAPK/S...

Sahay(Bikash),Patsey(Rebeca L),Eggers(Chri... PLoS Pathog 2010-02-24

...SOCS3, and CIS, thereby compromising the induction of tolerance in macrophages and engendering more severe and persisten...

Cannabinoids Delta(9)-tetrahydrocannabinol and cannabidiol differentially inh...

Kozela(Ewa),Pietr(Maciej),Juknat(Ana),Rimm... J Biol Chem 2010-02-08

...Socs3 gene, a main negative regulator of STATs and particularly of STAT3. However, both CBD and THC decreased the activa...

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