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Suppressor of cytokine signaling 3 inhibits antiviral IFN-beta signaling to e...

Akhtar(Lisa Nowoslawski),Qin(Hongwei),Muld... J Immunol 2010-09-22

...SOCS3 in human and murine macrophages in a NF-kappaB-dependent manner. SOCS3 expression attenuates the response of macro...

Gene expression profiling for molecular classification of multiple myeloma in...

Broyl(Annemiek),Hose(Dirk),Lokhorst(Henk),... Blood 2010-11-23

...SOCS3. To conclude, in addition to 7 clusters described in the UAMS classification, we identified 3 novel subsets of mul...

IFN gamma-dependent SOCS3 expression inhibits IL-6-induced STAT3 phosphorylat...

Bluyssen(Hans A R),Rastmanesh(M Mehdi),Til... Am J Physiol Cell Physiol 2010-08-19

...SOCS3). Therefore, cytokines that modulate SOCS3 expression might inhibit the anti-inflammatory effects of IL-6. We hypo...

Sequence of administration and methylation of SOCS3 may govern response to ge...

Middeldorf(Iris),Galm(Oliver),Osieka(Rainh... Am J Hematol 2010-07-21

...SOCS3 CpG island was found in 8/24 patients. There was a trend towards a higher RR and longer OS in patients with SOCS3 ...

Interleukin 11 is upregulated in uterine lavage and endometrial cancer cells ...

Yap(Joanne),Salamonsen(Lois A),Jobling(Tom... Reprod Biol Endocrinol 2010-10-07

...SOCS3 staining intensity did not differ between between each tumour and postmenopausal endometrial epithelium but SOCS3 ...

Gprc5a deletion enhances the transformed phenotype in normal and malignant lu...

Chen(Yulong),Deng(Jiong),Fujimoto(Junya),K... Cancer Res 2010-12-21

...Socs3, the endogenous Stat3 inhibitory protein, was higher in Gprc5a(+/+) than in Gprc5a(-/-) cells, and expression of t...

Modulation of SOCS protein expression influences the interferon responsivenes...

Lesinski(Gregory B),Zimmerer(Jason M),Krei... BMC Cancer 2010-06-14

...SOCS3 proteins was evaluated by immunoblot analysis in a panel of n = 10 metastatic human melanoma cell lines, in human ...

Extended anti-inflammatory action of a degradation-resistant mutant of cell-p...

Fletcher(Tynetta C),DiGiandomenico(Antonio... J Biol Chem 2010-06-29

...SOCS3) regulates the proinflammatory cytokine signaling mediated by the JAK/STAT signaling pathway. SOCS3 is rapidly ind...

SOCS3-mediated blockade of JAK/STAT3 signaling pathway reveals its major cont...

Dominguez(Elisa),Mauborgne(Annie),Mallet(J... J Neurosci 2010-05-04

...SOCS3, a physiologic inhibitory protein of JAK/STAT3, and analyzed its consequences in a preclinical model of neuropathi...

Possible involvement of signal transducers and activators of transcription 3 ...

Mingmalairak(Salin),Tohda(Michihisa),Murak... Biol Pharm Bull 2010-11-12

...Socs3) gene is up-regulated in non-LH animals. Since both StIP1 and Socs3 regulate the activity of Stat3 gene, these res...

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