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Chapman(Timothy M),Gillen(Kevin J),Wallace... Bioorg Med Chem Lett 2016-05-23

...ERCC1-XPF with high ligand efficiency, and elaboration of the hit gave compounds 36 and 37 which showed promising ERCC1-...

Chapman(Timothy M),Wallace(Claire),Gillen(... Bioorg Med Chem Lett 2016-05-23

A high throughput screen allowed the identification of N-hydroxyimide inhibitors of ERCC1-XPF endonuclease activity with...

Boccard(Sandra G),Marand(Sandie V),Geraci(... Oncotarget 2016-08-11

...ercc1, ercc2, mutyh, and pnkp significantly sensitized cells to chemotherapy, increasing cell death by up to 25%. In viv...

Sun(Yongjian),Wu(Yi),Li(Weicheng),Kong(Zhe... Int J Clin Exp Pathol 2016-06-14

...ERCC1 rs11615 and CC genotype of ERCC1 rs2298881 suffered a 3.16 and 3.57-fold increased hazards of death (For ERCC1 rs1...

Duan(Shanzhou),Tsai(Ying),Keng(Peter),Chen... Oncotarget 2016-08-16

...ERCC1 were significantly up regulated in cisplatin-treated A549sc and H157sc cells, but no increase was detected in A549...

Powrózek(T),Mlak(R),Krawczyk(P),Homa(I),Ci... Clin Transl Oncol 2016-10-25

...ERCC1, XPD, XPA, XPC, XRCC1, XPG, RRM1, BRCA1, STMN1 and the toxicity of first-line chemotherapy in NSCLC patients were ...

Kim(Miso),Ku(Ja Hyeon),Kwak(Cheol),Kim(Hye... PLoS One 2016-04-29

...ERCC1 expression achieved a clinical response, while 13 (50.0%) of 26 patients with high ERCC1 expression achieved a cli...

Reinardy(Helena C),Bodnar(Andrea G) Mutagenesis 2016-08-19

...ercc1, xpc, xrcc1, pcna, ogg1, parp1, parp2, ape, brca1, rad51, xrcc2, xrcc3, xrcc4, xrcc5, xrcc6 and gadd45), throughou...

Jin(Jian-Yue),Wang(Weili),Ten Haken(Randal... Radiother Oncol 2016-05-31

...ERCC1:rs11615) was found to predict dose-response. D50 values are 63.7 (90% CI: 53.5-66.3) Gy and 76.1 (90% CI: 71.3, 84...

Berardi(Rossana),Brunelli(Alessandro),Pagl... Oncotarget 2016-06-28

We aimed to analyze genotypes of VEGF-A, VEGFR2, Flt4, PDGFRα, HIF-1α and ERCC1 and their correlation with thymic tumor ...