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A young-onset dementia case associated with PDGFRβ mutation.

Totuk(O),Çelem(N),Sahin(S) J Alzheimers Dis Rep 2025-00-00

...PDGFRB c.1316G > A (p.Arg439Gln) variant. This report highlights a novel potential genetic contributor to vascular dysfu...

Pancreatic stellate cells have adipogenic and fibrogenic potentials but only ...

Soultoukis(GA),Leer(M),Kehm(R),Villacorta(... Redox Biol 2025-10-00

...Pdgfrb, which encode for the PDGF receptor alpha and -beta paralogs. Activated SCs, which display PDGF receptor alpha (P...

Melanoma microsatellites exhibit a metastatic signature by spatial transcript...

Warren(SJ),Xue(GR),Zhou(HM),Alomari(AK),Tu... Virchows Arch 2025-12-00

...PDGFRB, CDH1), vascular exit (ITGB2), survival at metastatic sites (C3, TGBFI), matrix remodeling (MMP9, VCAN, FN1, BGN)...

Exploring the mechanisms of hippocampal neurotoxicity induced by cypermethrin...

Yang(J),Ding(R),Qi(L),Bi(H),Li(J) Environ Toxicol Pharmacol 2025-08-00

...Pdgfrb) were finally identified. In addition, a miRNA-mRNA regulatory network was constructed, and expression patterns o...

Metabolic, transcriptomic, and proteomic adaptations in pancreatic ductal ade...

Guo(P),Fang(H),Shi(H),Zhang(J),Song(G),Fan... J Transl Med 2025-07-02

...PDGFRB, INO80E), indicative of enhanced signal transduction, cell cycle regulation, and DNA repair. Gene-protein interac...

Sex- and age- differences in the expression of critical blood-brain barrier r...

Mi(X),Ye(ZL),Zhang(XJ),Chen(XC),Dai(XM) Biol Sex Differ 2025-09-02

...Pdgfrb), microvessel marker (Cd31), basement membrane component (Col4a2), glycocalyx-related genes (Hs3st1, Extl2, and C...

From multi-omics to functional validation: the PTMRS stratifies TME and posit...

Liu(Y),Lu(C),Hua(L),Hao(H),Zhang(Q),Zou(Z)... Front Immunol None

...PDGFRB was validated as a core node within the PTMRS network: activation of PDGFRβ in human colonic fibroblasts promoted...

Nuclear Autoantigenic Sperm Protein Promotes Cardiac Regeneration and Repair ...

Wang(H),Zhao(D),Yang(T),Wang(W),Zhou(L),Su... FASEB J 2025-08-15

...PDGFRB), subsequently activating the downstream AKT/c-MYC pathway. Our study highlights the key role of NASP in facilita...

The Pdgfd-Pdgfrb axis orchestrates tumor-nerve crosstalk in pancreatic cancer...

Wang(P),Lester(N),Perrault(E),Su(J),Gong(D... bioRxiv 2025-08-31

...Pdgfrb signaling mediates PNI by coordinating multifaceted cancer-neuron-glia interactions and represents a promising th...

Single-cell transcriptome combined with genetic tracing reveals a roadmap of ...

Liao(M),Ye(Z),Zhao(Y),Nan(J),Liu(Y),Yao(X)... Proc Natl Acad Sci U S A 2025-09-16

...Pdgfrb+ RPE cells demonstrated significant morphological plasticity, transitioning toward a fibroblast-like phenotype, w...

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