Spencer-Jones(Nicola J),Wang(Xiaoling),Sni... Diabetes 2006-01-20

...PTPN1) and tested their effect on serum leptin, body fat, and measures of insulin sensitivity and the metabolic syndrome...

Cheyssac(Claire),Lecoeur(Cécile),Dechaume(... BMC Med Genet 2006-08-04

...PTPN1 gene located on chromosome 20q13 showing linkage with type 2 diabetes (T2D) in several populations. PTPN1 gene var...

Bence(Kendra K),Delibegovic(Mirela),Xue(Bi... Nat Med 2006-09-21

...Ptpn1(-/-)) mice. Neuronal Ptpn1(-/-) mice have reduced weight and adiposity, and increased activity and energy expendit...

Bento(Jennifer L),Palmer(Nicholette D),Myc... Diabetes 2005-01-12

The PTPN1 gene codes for protein tyrosine phosphatase 1B (PTP1B) (EC 3.1.3.48), which negatively regulates insulin signa...

Palmer(Nicholette D),Bento(Jennifer L),Myc... Diabetes 2005-01-12

Protein tyrosine phosphatase (PTP)-1B, encoded by the PTPN1 gene, catalyzes the dephosphorylation of proteins at tyrosyl...

Lu(Xiaoqing),Nechushtan(Hovav),Ding(Feiyin... Blood 2005-05-03

...PTPN1) and PTPN2, whose expression is significantly higher in ABC-like DLBCL. These differences in tyrosine phosphatase ...

Yang(Sang Hwa),Seo(Min Young),Jeong(Ha Jin... Clin Cancer Res 2005-05-12

...PTPN1, and ZNF217 was amplified in gastric cancer. Another group of 39 genes, whose sum of copy number change levels was...

Born(Martina),Quintanilla-Fend(Leticia),Br... J Pathol 2005-05-03

...PTPN1, ZNF217, and PFDN4) was prominent. A significant correlation between the expression of the tyrosine kinases PTK6 a...

Florez(Jose C),Agapakis(Christina M),Burtt... Diabetes 2005-08-04

Protein tyrosine phosphatase (PTP)-1B, encoded by the PTPN1 gene, inactivates the insulin signal transduction cascade by...

Ukkola(Olavi),Rankinen(Tuomo),Lakka(Timo),... Obes Res 2005-09-12

...PTPN1) affects the regulation of insulin signaling and energy metabolism. We studied whether polymorphisms in the PTPN1 ...