Zuhlke(Kimberly A),Johnson(Anna M),Tomlins(S… Prostate 2014-07-01

...SPOP.,We identified a novel SPOP missense mutation (N296I) in a man with prostate cancer diagnosed at age 43. This mutat...

Lin(Chuwen),Chen(Miao-Hsueh),Yao(Erica),Song… Dev Biol 2014-09-19

...Spop-mediated degradation of Gli2/3 by Sufu. Thus, controlling protein levels of all three Gli genes by Sufu is a conser...

Saar(Matthias),Zhao(Hongjuan),Nolley(Rosalie… Cancer Lett 2014-11-24

...SPOP mutation.

Jia(Deshui),Dong(Rui),Jing(Ying),Xu(Dan),Wan… Hepatology 2014-12-30

...SPOP, OR5I1, and CDC20B) influence HB cell growth. Moreover, we found that SPOP S119N is a loss-of-function mutation in ...

Theurillat(Jean-Philippe P),Udeshi(Namrata D… Science 2014-10-21

...SPOP, an E3 ubiquitin ligase substrate-binding protein. SPOP mutants impaired ubiquitylation of a subset of proteins in ...

Le Gallo(Matthieu),O'Hara(Andrea J),Rudd(Meg… Nat Genet 2013-02-13

...SPOP (8%), MAP3K4 (6%) and ABCC9 (6%). Overall, 36.5% of serous tumors had a mutated chromatin-remodeling gene, and 35% ...

Gyhagen(M),Bullarbo(M),Nielsen(T F),Milsom(I) BJOG 2013-02-13

...sPOP and UI.,Prevalence rate and risk of sPOP with or without concomitant UI.,Prevalence of sPOP was higher after vagina...

Kim(Min S),Je(Eun M),Oh(Ji E),Yoo(Nam J),Lee… APMIS 2013-08-26

...SPOP protein expression and somatic mutation of SPOP gene are features of cancers. In this study, we analyzed SPOP somat...

Stoehr(Robert),Taubert(Helge),Gaisa(Nadine T… J Pathol 2013-09-13

...SPOP, FOXA1 and MED12 mutations in prostate cancer. Nature Genet 2012; 44: 685-689). In more than 70% of prostate tumour...

Geng(Chuandong),He(Bin),Xu(Limei),Barbieri(C… Proc Natl Acad Sci U S A 2013-06-27

...SPOP substrate-binding cleft recently were identified in up to 15% of human PCs (making SPOP the gene most commonly affe...