Literature Search

Li(B),Zhao(L),Zhu(Q),Xie(S) Virus Res 2026-06-00

...Syk activation, evidenced by elevated p-ERK levels and abolished proliferation upon ERK/Syk inhibition (P < 0.001). No e...

Shin(JH),Akram(AW),Saba(E),Kim(MC),Kim(SD),P… J Ginseng Res 2026-05-00

...Syk. Additionally, G-Rs3 inhibited integrin αIIbβ3 activation, reduced platelet adhesion, and enhanced cyclic nucleotide...

Zhang(H),Yun(Q),Xu(Z),Wang(Y),Zhou(X),Deng(L… Eur J Pharmacol 2026-04-15

...SYK, and NF-κB serving as the hub genes. The expression of proteins in the TLR4/SYK/NF-κB pathway and inflammatory cytok...

Vikár(S),Mócsai(A) Front Immunol None

...Syk tyrosine kinase play a very important role in signaling by Fcγ-receptors, JAK-family kinases are crucial players in ...

Croden(J),Garcia-Manero(G),Chien(K),DiNardo(… Leuk Lymphoma 2026-06-00

...SYK inhibitor approved for immune thrombocytopenia, was evaluated in a phase 1 open-label study in previously treated lo...

Senevirathne(SE),Kanagy(WK),Hemmila(CR),Gree… J Immunol 2026-03-17

...Syk, drives second-messenger generation, and induces downstream Erk and Akt signaling and proinflammatory responses in m...

Fang(Y),Zhang(S),Zhu(Y),Xu(R),Fang(Z),Ling(L… Discov Oncol 2026-04-02

...SYK, and PGF) were supported by both replication in an independent cohort and strong colocalization. These 22 targets we...

Kim(B),Tate(MD),Karahan(H),Wijeratne(HRS),Sh… Neuron 2026-08-05

...Syk, Lyn, and Fcgr1. Furthermore, directly activating these genes rescues the impaired amyloid-beta (Aβ) uptake caused b...

Roskoski(R) Pharmacol Res 2026-05-00

...Syk) activate BTK. It then mediates the phosphorylation and activation of phospholipase Cγ2 (PLCγ2). The Ras/RAF/MEK/ERK...

Liu(X),Tian(X),Lin(J),Wang(Q),Zhang(L),Liu(Y… ACS Infect Dis 2026-05-08

...Syk/NF-κB signaling pathway. These findings indicate that miR-146a-5p modulates the inflammatory responses in FK, highli...