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Gab2 regulates cytoskeletal organization and migration of mammary epithelial ce…

Herrera Abreu(Maria Teresa),Hughes(William E… Mol Biol Cell 2011-07-21

...Vav2 phosphorylation and plasma membrane recruitment of p190A RhoGAP. Knockdown of p190A RhoGAP reversed Gab2-mediated e...

The immune molecule CD3zeta and its downstream effectors ZAP-70/Syk mediate eph…

Angibaud(Julie),Louveau(Antoine),Baudouin(St… J Neurochem 2011-12-23

...Vav2 pathway and a repression of neurite outgrowth. Conversely, cultured neurons lacking CD3ζ isolated from CD3ζ(-/-) mi...

TGFβ-induced early activation of the small GTPase RhoA is Smad2/3-independent a…

Papadimitriou(Elsa),Kardassis(Dimitris),Mous… Cell Physiol Biochem 2011-12-30

...Vav2 silencing via siRNA reduced the TGFβ-induced RhoA activation implying that the rapid Src/Vav2 stimulation was effec...

Variations in NTF4, VAV2, and VAV3 genes are not involved with primary open-ang…

Rao(Kollu N),Kaur(Inderjeet),Parikh(Rajul S)… Invest Ophthalmol Vis Sci 2010-10-19

Recently, the neurotrophin-4 (NTF4), VAV2 and VAV3 genes have been implicated in primary open-angle glaucoma (POAG) in t...

Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis.

Nischwitz(Sandra),Cepok(Sabine),Kroner(Antje… J Neuroimmunol 2010-10-19

...VAV2 gene and the gene for ZNF433.

Guanine exchange factor Vav2: a novel potential target for the development of d…

Holthusen(Kirsten),Gonzalez(Ana M),Meneses(P… Am J Ther 2010-02-24

...Vav2. We determined that the interaction of L2 with Vav2 was mediated by the N-terminus of L2 and independent of the N-t...

Distinct roles for Rho versus Rac/Cdc42 GTPases downstream of Vav2 in regulatin…

Duan(Lei),Chen(Gengsheng),Virmani(Sumeet),Yi… J Biol Chem 2010-01-26

...Vav2 phenotype, whereas in contrast, RhoA knockdown intensified the Vav2-induced disruption of acini, leading to more ag...

Vav3-deficient mice exhibit a transient delay in cerebellar development.

Quevedo(Celia),Sauzeau(Vincent),Menacho-Márq… Mol Biol Cell 2010-09-08

...Vav2-deficient mice do not show any of those defects. Using primary neuronal cultures, we show that Vav3 is important fo...

VAV2 regulates epidermal growth factor receptor endocytosis and degradation.

Thalappilly(S),Soubeyran(P),Iovanna(J L),Dus… Oncogene 2010-05-11

...Vav2 on EGFR degradation is dependent on its guanine nucleotide exchange function. Knockdown of Vav2 in HeLa cells enhan...

VAV2 and VAV3 as candidate disease genes for spontaneous glaucoma in mice and h…

Fujikawa(Keiko),Iwata(Takeshi),Inoue(Kaoru),… PLoS One 2010-09-30

...Vav2/Vav3-deficient mice, and to a lesser degree Vav2-deficient mice, show early onset of iridocorneal angle changes and...

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