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Expression of IL-24, an activator of the JAK1/STAT3/SOCS3 cascade, is enhance...

Andoh(Akira),Shioya(Makoto),Nishida(Atsush... J Immunol 2009-08-20

...SOCS3 expression in HT-29 colonic epithelial cells. IL-24 did not modulate the proliferation of HT-29 cells, but signifi...

TGF-beta promotes Th17 cell development through inhibition of SOCS3.

Qin(Hongwei),Wang(Lanfang),Feng(Ting),Elso... J Immunol 2009-08-20

...SOCS3 promoter activity in T cells. Also, SOCS3 small interfering RNA knockdown partially compensates for the action of ...

Restoration of SOCS3 suppresses human lung adenocarcinoma cell growth by down...

Yu(Zu-Bin),Bai(Li),Qian(Pin),Xiao(Yin-Bin)... Cell Biol Int 2009-12-03

SOCS3 is regarded as a major negative regulator of STAT3. Recent evidence indicates that SOCS3 regulates strength and du...

Respiratory syncytial virus proteins modulate suppressors of cytokine signali...

Oshansky(Christine M),Krunkosky(Thomas M),... Viral Immunol 2009-06-16

...SOCS3 regulation of the type I interferon (IFN) response in normal fully-differentiated human bronchial epithelial cells...

Site-specific ubiquitination determines lysosomal sorting and signal attenuat...

Wölfler(Albert),Irandoust(Mahban),Meenhuis... Traffic 2009-10-05

...SOCS3 drives lysosomal degradation of the granulocyte colony-stimulating factor receptor (G-CSFR), depending on SOCS3-me...

Individuality and epigenetics in obesity.

Campión(J),Milagro(F I),Martínez(J A) Obes Rev 2009-08-18

...SOCS3, in inflammation, and COX7A1 LPL, CAV1, and IGFBP3, in intermediate metabolism and insulin signalling. The identif...

Status of Stat3 in an ovalbumin-induced mouse model of asthma: analysis of th...

Paul(Bholanath),Mishra(Vani),Chaudhury(Bhu... Int Arch Allergy Immunol 2009-02-09

...Socs3 expression profiles were monitored in OVA/OVA and Stat3- and Socs3-silenced OVA/OVA mice. Furthermore, expression ...

SOCS3 and IRS-1 gene expression differs between genotype 1 and genotype 2 hep...

Persico(Marcello),Russo(Roberta),Persico(E... Clin Chem Lab Med 2009-12-08

...SOCS3, IRS-1 and phospho-AKT mediated by the genotype 1b virus.,Up-regulation of the SOCS3 gene might be one of the mech...

Salmonella disrupts lymph node architecture by TLR4-mediated suppression of h...

St John(Ashley L),Abraham(Soman N) Nat Med 2009-11-23

...Socs3) is upregulated, which negatively regulates mothers against decapentaplegic homolog-3 (Smad3)-initiated production...

SOCS3 in T and NKT cells negatively regulates cytokine production and amelior...

Nakaya(Mako),Hashimoto(Masayuki),Nakagawa(... J Immunol 2009-12-22

...SOCS3 in T and NKT cells suppressed ConA-induced hepatitis using T and NKT cell-specific SOCS3 transgenic (Lck-SOCS3 Tg)...

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