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Gene expression profiling distinguishes JAK2V617F-negative from JAK2V617F-pos...

Puigdecanet(E),Espinet(B),Lozano(J J),Sumo... Leukemia 2008-08-26

...SOCS3, ID2, GADD45B, KLF5, TNF, LAMB3, HRH4, TAGAP and TRIB1) showed an abnormal expression pattern. In this group of pa...

Correlation analysis of gene expression and clinical chemistry to identify bi...

Casey(W M),Brodie(T),Yoon(L),Ni(H),Jordan(... Biomarkers 2008-08-18

...Socs3 (suppressor of cytokine signalling 3) and Mid1ip1 (Mid1 interacting protein 1). The physiological function of thes...

Neuroinflammatory response to lipopolysaccharide is exacerbated in mice genet...

Aid(Saba),Langenbach(Robert),Bosetti(Franc... J Neuroinflammation 2008-09-22

...SOCS3).,These results show that inhibiting COX-2 activity can exacerbate the inflammatory response to LPS, possibly by i...

The SOCS box domain of SOCS3: structure and interaction with the elonginBC-cu...

Babon(Jeffrey J),Sabo(Jennifer K),Soetopo(... J Mol Biol 2008-09-05

...SOCS3 binds to elonginBC and cullin5 with high affinity. The SOCS3-elonginBC interaction was further characterised by de...

Activation of peroxisome proliferator-activated receptor beta/delta inhibits ...

Rodríguez-Calvo(Ricardo),Serrano(Lucía),Co... Diabetes 2008-09-04

...SOCS3) pathway. This effect was associated with the capacity of GW501516 to impede LPS-induced NF-kappaB activation. Sec...

Unique expression of suppressor of cytokine signaling 3 is essential for clas...

Liu(Yu),Stewart(Keith N),Bishop(Eileen),Ma... J Immunol 2008-06-04

...SOCS3 expressing cells. Macrophages in which SOCS3 was knocked down by short interfering RNA responded to IFN-gamma and ...

Long-term interleukin-1alpha treatment inhibits insulin signaling via IL-6 pr...

Uno(T),He(J),Usui(I),Kanatani(Y),Bukhari(A... Horm Metab Res 2008-03-26

...SOCS3, an endogenous inhibitor of insulin signaling, was dramatically augmented 4 hours after IL-1alpha treatment. Conco...

Attenuation of signaling and nitric oxide production following prolonged lept...

Blanquicett(Carmelo),Graves(Anitra),Kleinh... J Investig Med 2008-04-10

...SOCS3), xanthine oxidase (XO), and the reduced nicotinamide adenine dinucleotide (NADPH) oxidase components p22phox, p67...

Different regulation of T helper 1- and T helper 2-promoting cytokine signall...

Böttcher(Ingo),Bellinghausen(Iris),König(B... Immunology 2008-02-12

...SOCS3, T-bet and GATA3 were analysed by quantitative real-time polymerase chain reaction. Exposure of DC to protein alle...

Demonstration of cooperative contribution of MET- and EGFR-mediated STAT3 pho...

Seki(Ekihiro),Kondo(Yuichi),Iimuro(Yuji),N... J Hepatol 2008-04-08

...SOCS3, potent negative regulators of STAT3 signaling, selectively in hepatocytes.,We generated recombinant adenoviruses ...

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