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SOCS3 suppresses AP-1 transcriptional activity in neuroblastoma cells through...

Miao(Tizong),Wu(Dongsheng),Zhang(Yi),Bo(Xu... Mol Cell Neurosci 2008-04-25

...SOCS3 (suppressor of cytokine signaling) inhibited and mutant SOCS3 (with an inactivating point mutation in amino acid 2...

SOCS3 negatively regulates the gp130-STAT3 pathway in mouse skin wound healin...

Zhu(Bing-Mei),Ishida(Yuko),Robinson(Gertra... J Invest Dermatol 2008-06-24

...Socs3 and gp130 genes restored normal wound healing. Moreover, deletion of Socs3 only in keratinocytes caused impaired w...

TAMpering with toll-like receptor signaling.

O'Neill(Luke A J) Cell 2008-02-14

...SOCS3.

TAM receptors are pleiotropic inhibitors of the innate immune response.

Rothlin(Carla V),Ghosh(Sourav),Zuniga(Elin... Cell 2008-02-14

...SOCS3. These results illuminate a self-regulating cycle of inflammation, in which the obligatory, cytokine-dependent act...

Substitution of pseudokinase domain residue Val-617 by large non-polar amino ...

Dusa(Alexandra),Staerk(Judith),Elliott(Joa... J Biol Chem 2008-06-17

...SOCS3), a mechanism by which JAK2 V617F overcomes inhibition by SOCS3. The V617W mutant induced a myeloproliferative dis...

Perturbed thymopoiesis in vitro in the absence of suppressor of cytokine sign...

Croom(Hayley A),Izon(David J),Chong(Mark M... Mol Immunol 2008-07-02

...SOCS3. Here, we find that both SOCS1 and SOCS3 are expressed during early thymopoiesis, with expression coincident durin...

Loss of suppressor of cytokine signaling 1 in helper T cells leads to defecti...

Tanaka(Kentaro),Ichiyama(Kenji),Hashimoto(... J Immunol 2008-06-10

...SOCS3-overexpressed cells, indicating that suppression of Smads was independent of SOCS3. Therefore, SOCS1 is necessary ...

SOCS-1 protects against Chlamydia pneumoniae-induced lethal inflammation but ...

Yang(Tangbin),Stark(Patrik),Janik(Katrin),... J Immunol 2008-06-10

...SOCS3, and the role of SOCS1 during infection with C. pneumoniae in mice. Bone marrow-derived macrophages (BMM) and dend...

SOCS3 in liver regeneration and hepatocarcinoma.

Elliott(Joanne) Mol Interv 2008-05-22

...SOCS3 has recently improved and indicates that SOCS3 is critical in modulating cytokine-mediated and neoplastic-prolifer...

Effects of subcutaneous leptin injections on hypothalamic gene profiles in le...

Duan(Jiuhua),Choi(Yang-Ho),Hartzell(Diane)... Obesity (Silver Spring) 2008-04-10

...SOCS3) compared with ob/ob controls. Leptin treatment dramatically up-regulated hypothalamic mRNA level of POMC1 in both...

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