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The local and systemic inflammatory transcriptome after acute kidney injury.

Grigoryev(Dmitry N),Liu(Manchang),Hassoun(... J Am Soc Nephrol 2008-03-26

...Socs3, Saa3, Lcn2, and Il1r2. Functional genomic analysis of these genes suggested that IL-10 and IL-6 signaling was inv...

Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interfa...

Bullock(Alex N),Rodriguez(Maria C),Debrecz... Structure 2008-03-11

...SOCS3 family C terminus in a distinct SH2-SOCS box interface that facilitates further interdomain packing between the ex...

Investigation of the interleukin (IL)-4/IL-4 receptor system in promyelocytic...

Ratthé(Claude),Girard(Denis) Br J Haematol 2008-04-23

...SOCS3) protein level in the presence of the proteasome inhibitor MG132 exclusively in PLB-985D cells. As the IL-4Ralpha ...

Regulation of interleukin-6-induced hepatic insulin resistance by mammalian t...

Kim(Jeong-Ho),Kim(Jae Eun),Liu(Hui-Yu),Cao... J Biol Chem 2008-03-20

...SOCS3 expression is inhibited by rapamycin, and ectopic expression of SOCS3 blocks the ability of rapamycin to enhance i...

Different regulation of T helper 1- and T helper 2-promoting cytokine signall...

Böttcher(Ingo),Bellinghausen(Iris),König(B... Immunology 2008-02-12

...SOCS3, T-bet and GATA3 were analysed by quantitative real-time polymerase chain reaction. Exposure of DC to protein alle...

Regulation of liver regeneration and hepatocarcinogenesis by suppressor of cy...

Riehle(Kimberly J),Campbell(Jean S),McMaha... J Exp Med 2008-01-30

...Socs3 hepatocyte-specific knockout (Socs3 h-KO) mice to directly study the role of SOCS3 during liver regeneration after...

The role of SOCS3 in modulating leukaemia inhibitory factor signalling during...

Boyle(Kristy),Robb(Lorraine) J Reprod Immunol 2008-03-25

...SOCS3 die at midgestion due to placental insufficiency. SOCS3-null placentae have increased numbers of mature trophoblas...

Socs3 maintains the specificity of biological responses to cytokine signals d...

Croker(Ben A),Mielke(Lisa A),Wormald(Sam),... Exp Hematol 2008-08-19

...Socs3). Mice with Socs3 deleted specifically in hematopoietic cells succumb to severe neutrophil and macrophage-driven i...

Activation of peroxisome proliferator-activated receptor beta/delta inhibits ...

Rodríguez-Calvo(Ricardo),Serrano(Lucía),Co... Diabetes 2008-09-04

...SOCS3) pathway. This effect was associated with the capacity of GW501516 to impede LPS-induced NF-kappaB activation. Sec...

Leptin inhibits mitogen-induced proliferation of peripheral T lymphocytes fro...

Ahmed(Mohamed),Kimura(Kazuhiro),Soliman(Mo... Vet J 2008-07-10

...SOCS3 mRNA expression. Simultaneous treatment with mitogens and leptin enhanced IFNgamma mRNA expression but decreased I...

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