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TP53 BRCA1 CRISPR single-cell cancer

Takahashi(Yutaka),Takahashi(Michiko),Carpi... Mol Endocrinol 2008-09-03

...SOCS3) inhibits leukemia-inhibitory factor (LIF) signaling and acts as a negative regulator. Deletion of SOCS3 causes em...

Zeng(Bin),Li(Haijie),Liu(Yu),Zhang(Zhuohan... Cancer Res 2008-08-05

...SOCS3 transcript and protein levels. The ectopic expression of SOCS3 in both the macrophage cell line RAW264.7 and BMDCs...

Zhu(Pengxiang),Hata(Ryuji),Cao(Fang),Gu(Fe... FASEB J 2008-11-18

...SOCS3. Promoter assay revealed transactivation of Stat3 function in NSCs by Mi cells. Gene expression study revealed tha...

Mitra(Mayurranjan S),Donthamsetty(Shashiki... Toxicol Appl Pharmacol 2008-10-02

...SOCS3 further downregulated the cardioprotective JAK/STAT3 pathway. In conclusion, HFD-induced obese rats are highly sen...

Ozawa(Yoko),Nakao(Keiko),Kurihara(Toshihid... J Biol Chem 2008-10-20

...SOCS3), a negative feedback regulator of STAT3 activation. SOCS3 was expressed mainly in photoreceptor cells in the reti...

Dimitriou(Ioannis D),Clemenza(Liliana),Sco... Immunol Rev 2008-11-03

...SOCS3 to negatively regulate activation and/or differentiation pathways in macrophages, dendritic cells, and T lymphocyt...

Baetz(Andrea),Koelsche(Christian),Strebovs... FASEB J 2008-12-31

...SOCS3 resulted in loss of nuclear localization. Fusion of the SOCS1-NLS to cytokine-inducible SH2 region containing prot...

Kim(Byung Hak),Yin(Chang-Hong),Guo(Qianxu)... Mol Cancer Ther 2008-10-22

...SOCS3 in a dose- and time-dependent manner. In addition, AUH-6-96-treated L540 cells showed decreased expression of pers...

Hou(Tieying),Ray(Sutapa),Lee(Chang),Brasie... J Biol Chem 2008-12-23

...socs3 promoter as efficiently as those expressing STAT3-full length. We previously reported that the STAT3 NH(2)-termina...

Sabio(Guadalupe),Das(Madhumita),Mora(Alfon... Science 2008-12-22

...SOCS3, a protein that induces hepatic insulin resistance. Thus, JNK1 activation in adipose tissue can cause insulin resi...

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