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Loss-of-Function Mutation in APC2 Causes Sotos Syndrome Features.

Almuriekhi(Mariam),Shintani(Takafumi),Fahi... Cell Rep 0000-00-00

...Apc2 mice, and this defect was rescued by the forced expression of Apc2. Thus, APC2 is a crucial target of NSD1, which p...

Heparan sulfate regulates the number and centrosome positioning of Drosophila...

Levings(Daniel C),Arashiro(Takeshi),Nakato... Mol Biol Cell 0000-00-00

...Apc2, a component of the centrosome-anchoring machinery, at the hub-GSC interface. This perturbation of the centrosome-a...

The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the ...

Croy(Heather E),Fuller(Caitlyn N),Giannott... J Biol Chem 0000-00-00

...APC2, and that this motif is conserved in human APC2, but not human APC1. In addition, we find that APC2 can recruit TNK...

Discovery of candidate tumor biomarkers for treatment with intraperitoneal ch...

Seagle(Brandon-Luke L),Eng(Kevin H),Yeh(Ju... Sci Rep 0000-00-00

...APC2 and high expression of FUT9 was associated with 5.5 and 7.2 months, respectively, decreased OS after IP compared to...

Functional redundancy between Apc and Apc2 regulates tissue homeostasis and p...

Daly(C S),Shaw(P),Ordonez(L D),Williams(G ... Oncogene 0000-00-00

...APC2 in the pathogenesis of human breast cancer are ill-defined, but our analysis of publically available array data set...

Proteomic analysis reveals APC-dependent post-translational modifications and...

Blundon(Malachi A),Schlesinger(Danielle R)... Development 0000-00-00

...Apc2 causes protein isoform changes reflecting misregulation of post-translational modifications (PTMs), which are not d...

Wnt Signaling and Survival of Women With High-Grade Serous Ovarian Cancer: A ...

Seagle(Brandon-Luke L),Dandapani(Monica),Y... Int J Gynecol Cancer 0000-00-00

...APC2 was associated with decreased overall survival (HR, 1.22; 95% CI, 1.05-1.42; P = 0.009) and progression-free surviv...

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