...CSF1R) cause CSF-1R-related leukoencephalopathy (CRL), an adult-onset neurodegenerative disease that is modeled in the C...
...CSF1R inhibitor can inhibit the tumor growth of recurrent GCTB. Targeting CSF1R and alleviating T cell exhaustion may pr...
...Csf1r, CD84, Tmem173, Homer1, Grm2 and Supt7l. Notably, female injured mice showed differential improvements in select p...
...CSF1R blockade), disrupting checkpoint signals (anti-CD47/SIRPα, PD-1/PD-L1 inhibitors), and reprogramming M2 TAMs towar...
...CSF1R inhibitors), combining TAM-targeted therapy with immune checkpoint inhibitors, and developing novel approaches suc...
The colony-stimulating factor 1 receptor (CSF1R) inhibitor PLX5622 has been widely used to deplete microglia for functio...
...CSF1R axis in pathology. These findings provide in vivo evidence of macrophage regulation of fibroblasts, revealing a bi...
...Csf1rI792T/+ mice exhibit hallmark features of CSF1R-related disorder (CSF1R-RD), including cognitive deficits, ventricu...
...CSF1R (also known as CD115) expression. Further analysis showed that PαS cells cultured in macrophage differentiation me...
...Csf1r+ macrophages. Cell-cell communication analyses identified Csf1r+ macrophages as suppressors of these NK- and effec...
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