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Disruption of CSF-1 receptor-mediated metal ion homeostasis in the murine bra...

Chițu(V),Alvarenga(J),Chen(W),Reynolds(D),... J Clin Invest 2026-05-01

...CSF1R) cause CSF-1R-related leukoencephalopathy (CRL), an adult-onset neurodegenerative disease that is modeled in the C...

The single cell transcriptomic landscape of recurrent giant cell tumor of bon...

Hu(X),Wu(H),Zheng(B),Liang(C),Shi(B),Ye(Q)... J Genet Genomics 2026-08-00

...CSF1R inhibitor can inhibit the tumor growth of recurrent GCTB. Targeting CSF1R and alleviating T cell exhaustion may pr...

Neuroinflammatory and functional outcomes after TBI are sex-dependent: Lesson...

Royal(T),Ahluwalia(P),Gulhane(M),Salles(EL... Neurochem Int 2026-05-00

...Csf1r, CD84, Tmem173, Homer1, Grm2 and Supt7l. Notably, female injured mice showed differential improvements in select p...

Macrophage-centered immunotherapy for osteosarcoma: mechanisms, repolarizatio...

Li(Z),Lin(D),Wu(L),Xu(W),Zhang(H),Zhuang(Z... World J Surg Oncol 2026-03-07

...CSF1R blockade), disrupting checkpoint signals (anti-CD47/SIRPα, PD-1/PD-L1 inhibitors), and reprogramming M2 TAMs towar...

Diversity and function of tumor-associated macrophages in brain metastases: m...

Ma(Y),Wang(H),Dou(X),Li(Q) Front Immunol None

...CSF1R inhibitors), combining TAM-targeted therapy with immune checkpoint inhibitors, and developing novel approaches suc...

More than microglial depletion: PLX5622 activates the hepatic constitutive an...

Cao(K),Cheng(W),Qiu(L),Wang(Z),Zhao(Y),Yua... Neuron 2026-04-15

The colony-stimulating factor 1 receptor (CSF1R) inhibitor PLX5622 has been widely used to deplete microglia for functio...

Reciprocal regulation of fibroblast-macrophage equilibrium governs skin integ...

Vollmers(AC),Wu(SZ),Altieri(A),McCartney(E... Nat Immunol 2026-04-00

...CSF1R axis in pathology. These findings provide in vivo evidence of macrophage regulation of fibroblasts, revealing a bi...

A strategy of microglia replacement alleviates microgliopathy in a CSF1R I794...

Li(X),Hu(B),Wu(C),Wang(Z),Fan(H),Guan(X),X... Cell Rep Med 2026-03-17

...Csf1rI792T/+ mice exhibit hallmark features of CSF1R-related disorder (CSF1R-RD), including cognitive deficits, ventricu...

Differentiation of mesenchymal stem/stromal cells into CD45+ macrophage-like ...

Rusch(RM),Mabuchi(Y),Morikawa(S),Ogawa(Y),... iScience 2026-03-20

...CSF1R (also known as CD115) expression. Further analysis showed that PαS cells cultured in macrophage differentiation me...

CSF-1R inhibition and lenalidomide synergize to promote myeloma control after...

Minnie(SA),Ho(K),Boiko(JR),Adams(RC),Ensbe... Blood 2026-06-04

...Csf1r+ macrophages. Cell-cell communication analyses identified Csf1r+ macrophages as suppressors of these NK- and effec...

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