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The role of conformational selection in the molecular recognition of the wild...

Fadda(Elisa) Proteins 2016-10-31

...ERCC1, falls in this challenging study category. The microsecond molecular dynamics (MD) simulations, discussed in this ...

Expression of ERCC1, TYMS, RRM1, TUBB3, non-muscle myosin II, myoglobin and M...

Jiang(Haijiao),Wang(He),Wang(Shiyu),Pei(Zh... Mol Med Rep 2016-03-04

The association between the expression of excision repair cross‑complementing gene 1 (ERCC1), thymidylate synthase (TYMS...

Genetic variability of genes in NER pathway influences the treatment outcome ...

Xue(Ming-Hui),Li(Guang-Yan),Wu(Xin-Jun),Zh... Int J Clin Exp Pathol 2016-04-21

We performed a study to investigate the role of ERCC1, ERCC2, ERCC5, XPA and XPC polymorphisms from perspective of the w...

Randomized phase II study evaluating veliparib (ABT-888) with temozolomide in...

Middleton(M R),Friedlander(P),Hamid(O),Dau... Ann Oncol 2016-07-07

...ERCC1 expression had longer PFS when TMZ was combined with veliparib. Toxicities were as expected for TMZ. The frequenci...

Enhancement of oxaliplatin sensitivity in human colorectal cancer by hyperici...

Lin(Shengchao),Lei(Kecheng),Du(Wenpei),Yan... Int J Biochem Cell Biol 2016-10-12

...ERCC1 and XPF, two critical enzymes involved in nucleotide excision repair (NER) pathway. GSH monoethyl ester (GSH-EE) a...

Comprehensive multiplatform biomarker analysis of 199 anal squamous cell carc...

Smaglo(Brandon G),Tesfaye(Anteneh),Halfdan... Oncotarget 2016-10-11

...ERCC1 (resistance to platinum-based chemotherapy), and thymidylate synthase (resistance to fluoropyrimidines) were also ...

CYP39A1 polymorphism is associated with toxicity during intensive induction c...

Melchardt(Thomas),Hufnagl(Clemens),Magnes(... BMC Cancer 2016-06-29

...ERCC1-rs3212986, rs11615, XRCC1-rs25487) or with docetaxel caused toxicity (CYP39A1-rs7761731, SLCO1B3-rs11045585) were ...

Genetic Polymorphisms in XRCC1, CD3EAP, PPP1R13L, XPB, XPC, and XPF and the R...

Xue(Ping),Gao(Lin),Xiao(Sha),Zhang(Guopei)... PLoS One 2016-06-26

...ERCC1 (Excision repair cross complementation group 1) is located on chromosome 19q13.2-3 and participates in the crucial...

Genetic variability of DNA repair mechanisms in chemotherapy treatment outcom...

Zhong(G),Li(H K),Shan(T),Zhang(N) Genet Mol Res 2016-09-15

We investigate whether three common polymorphisms in ERCC1 and ERCC2 are predictor factors for the chemotherapy response...

Correlation of ERCC1 expression in peripheral blood lymphocytes with outcomes...

Zhang(Y Y),Gu(K S),Wu(H Y),Yang(F),Bu(L J)... Genet Mol Res 2016-09-15

...ERCC1 (median DFS, 18 vs 10 months, P = 0.006; median OS, 30 vs 17 months, P = 0.012). In PBLs, high expression of ERCC1...

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