Kim(Bogyou),Nam(Hye Jin),Pyo(Ki Eun),Jang(Mi… Biochem Biophys Res Commun 2012-01-27

...SPOP adaptor protein. Intriguingly, BRMS1 turns out to be a potent substrate that is ubiquitinated by the Cul3-SPOP comp...

Choo(Yin Yin),Boh(Boon Kim),Lou(Jessica Jie … Mol Biol Cell 2012-07-30

...SPOP to Cul3, suggesting it may not function to facilitate the exchange of Cul3 substrate receptors. Our results indicat...

Liu(Yanhong),Melin(Beatrice S),Rajaraman(Pre… Hum Genet 2012-10-15

...SPOP rs650461 (P = 0.025). In the combined analysis of discovery and replication studies, the strongest associations wer...

Errington(Wesley J),Khan(M Qasim),Bueler(Ste… Structure 2012-11-02

...SPOPL. In combination, SPOP and SPOPL (SPOP-like) form a molecular rheostat that can fine-tune E3 ubiquitin ligase activ...

Barbieri(Christopher E),Baca(Sylvan C),Lawre… Nat Genet 2012-08-03

...SPOP was the most frequently mutated gene, with mutations involving the SPOP substrate-binding cleft in 6-15% of tumors ...

Li(C),Ao(J),Fu(J),Lee(D-F),Xu(J),Lonard(D),O… Oncogene 2011-12-09

...SPOP), a cullin 3 (CUL3)-based ubiquitin ligase, is responsible for SRC-3 ubiquitination and proteolysis. SPOP interacts...

Claiborn(Kathryn C),Sachdeva(Mira M),Cannon(… J Clin Invest 2010-11-10

...SPOP) is a nuclear protein that inhibits Pdx1 transactivation. Here, we show that Pcif1 targets Pdx1 for ubiquitination ...

Wen(Xiaohui),Lai(Cary K),Evangelista(Marie),… Mol Cell Biol 2010-04-28

...SPOP/Cul3 complex. In fact, full-length Gli3 disappears with faster kinetics than the Gli3 repressor, the latter not req...

Zhang(Qing),Shi(Qing),Chen(Yongbin),Yue(Tao)… Proc Natl Acad Sci U S A 2010-02-12

...SPOP. Our results provide a mechanistic insight into how HIB/SPOP recognizes its substrates and have important implicati...

Choo(Kong-Bung),Chuang(Trees-Juen),Lin(Wan-Y… Gene 2010-06-08

...SPOP paralog, designated as SPOP-like (SPOPL), in the human and rodent genomes. Ka/Ks analysis indicates that the SPOPL ...