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Crosstalk Between Clec7a and TLR4 Immune Pathway Drives Renal Damage in a Cispl…

Zhang(W),Xue(F),Shi(X),Fu(H),Shi(W),Guan(C),… FASEB J 2026-04-15

...Syk and TLR4/NF-κB promotes and sustains the inflammatory phenotypes of M1 macrophages, contributing to damage in AKI. T...

Evodiamine protects against lung ischemia-reperfusion injury by attenuating SYK…

Peng(W),Ge(B),Zhang(R),Liu(Y),Tong(C),Dong(C) Pulm Pharmacol Ther 2026-06-00

...SYK inhibitor BAY61-3606, or the combination. Compared with I/R alone, treatment reduced histopathological damage, infla...

Methylation and expression dynamics in broiler liver following in-ovo sodium bu…

Beldowska(A),Pietrzak(E),Dunisławska(A) J Vet Res 2026-03-00

...SYK and TNFRSF14. Sodium butyrate stimulation changed gene expression levels. Upregulation was noted of ANGPTL4 and NR4A...

[Advances in research on the mechanisms of reactive oxygen species in platelet …

Shen(RY),Xu(KL),Qiao(JL),Fu(P) Zhonghua Xue Ye Xue Za Zhi 2026-03-14

...Syk) -dependent and Syk-independent pathways. In addition, the protease-activated receptor (PAR) signaling pathway not o...

Functional genomic profiling of schizophrenia-associated genes reveals key micr…

Horng(JE),McCrea(LT),Batorsky(RE),Bowen(JJ),… Neuropsychopharmacology 2026-08-00

...SYK, ITGB2, ITGAM, and IRF8, modulated phagocytosis and altered morphological properties consistent with activation stat...

Early blood DNA methylation patterns associated with glycemic progression in a …

Satheesh(G),Asokan(AK),Vijayakumar(G),Rajave… Clin Epigenetics 2026-04-16

...SYK, ZNF516) in individuals who later developed T2DM, while those progressing to prediabetes exhibited six hypermethylat...

Metabolomics profiling of acute myelogenous leukemia patients to identify syste…

Brattås(MK),Hatfield(KJ),Paulsen Rye(K),Reik… Metabolomics 2026-04-17

...SYK) is crucial for leukemic cell survival and proliferation, and SYK inhibition is being explored in AML therapy. This ...

The contributions of TLR2, TLR8 and TLR3 to direct and antibody-dependent enhan…

Ter Ellen(BM),Punekar(M),Castillo(JA),Valdés… Npj Viruses 2026-04-17

...SYK). Blocking CD32 or SYK reduced antibody-enhanced infection to direct infection levels, whereas TLR2 inhibition aboli...

Chronic Eosinophilic Leukemia Presenting as Treatment-Refractory Nodular Scleri…

Ji(BC),Aung(T),Castellino(J),Kahlon(KS),Tsui… Cureus 2026-03-00

We report the first documented case of chronic eosinophilic leukemia (CEL) with ETV6-SYK gene rearrangement manifesting ...

Low-density neutrophil heterogeneity and spleen tyrosine kinase as therapeutic …

Teague(HL),Knabe(L),S Da Cruz(R),Yao(X),Alle… JCI Insight 2026-06-08

...SYK+ LDNs associated with increased levels of intracellular myeloperoxidase (MPO) and soluble biomarkers. Furthermore, S...

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