Literature Search

Gallagher(A),Wilson(AV),Lawal(S),Sanghvi(H),… eNeuro 2026-08-24

...Tsc2 haploinsufficiency in oxytocin-responsive cells, males displayed intact acquisition but generalized avoidance at bo...

Ausavarungnirun(C),Usama(M),Ngov(D),Badami(A… Am J Surg Pathol 2026-09-02

...TSC2 gene make it likely that TSC2-mutated thyroid carcinomas have been underdiagnosed so far. We suggest that TSC2-muta...

Zhao(J),Jiang(C),Luo(Y),Lin(X),Bai(Y),Meng(K… Biol Reprod 2026-08-31

...tsc2, atrx, and rad21b. RNA pulldown assays in zebrafish testes identified 486 potential THOR-interacting proteins prima...

Herini(ES),Triono(A),Iskandar(K),Nugrahanto(… Neurogenetics 2026-08-31

...TSC2, CC2D2A, and WDFY3, and two variants of uncertain significance were identified in CC2D2A and ATP6V1A. Among the fiv...

Raney(S),Karunamurthy(A),Ho(J),Bubar(R),Mohe… Genes Chromosomes Cancer 2026-09-00

...TSC2, or FLCN alteration was identified. These findings expand the molecular spectrum of PEComa and support the emerging...

Chen(X),Gao(H),Wu(W),Shi(P),Chen(Y),Zhang(A)… Adv Sci (Weinh) 2026-08-27

...TSC2), mediating its degradation. TSC2 loss relieves mechanistic target of rapamycin complex 1 (mTORC1) inhibition, resu...

Utami(KH),Yusof(NABM),Ramaswamy(Y),Tay(SKH),… Mol Neurobiol 2026-09-08

...TSC2KO, and FMR1/TSC2 dKO neurons. Neuronal transcriptomes were profiled by RNA-seq, integrating ERK, mTOR, FMRP targets...

He(S),Yang(J),Yang(J),Li(C),Shen(J),Ye(X),Li… Front Med (Lausanne) 2026-00-00

Acquired resistance to mTOR inhibition remains a major challenge in TSC2-mutant metastatic epithelioid angiomyolipoma (E...

Kuang(S),Liu(T),Wei(Z),Xu(J),Han(J),Wang(J),… Adv Sci (Weinh) 2026-01-00

...TSC2 conditional knockout (CKO) mouse models, as well as TSC2-KO cell models, are established. In vivo experiments demon...

Hartwich(TMP),Choi(S),Hwang(A),Bellone(S),Pa… Proc Natl Acad Sci U S A 2026-02-03

...TSC2, STK11). Finally, in an activating NRAS-mutant (p.Q61R) HG-ESS xenograft, the combination of MEK and FAK inhibition...