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Identification of a nuclear localization signal in suppressor of cytokine sig...

Baetz(Andrea),Koelsche(Christian),Strebovs... FASEB J 2008-12-31

...SOCS3 resulted in loss of nuclear localization. Fusion of the SOCS1-NLS to cytokine-inducible SH2 region containing prot...

Exercise-induced activation of STAT3 signaling is increased with age.

Trenerry(Marissa K),Carey(Kate A),Ward(Ali... Rejuvenation Res 2008-11-18

...SOCS3 mRNA, cellular protein abundance was suppressed. SOCS3 protein is an important negative regulator of STAT3 activat...

Putting out the fire: coordinated suppression of the innate and adaptive immu...

Dimitriou(Ioannis D),Clemenza(Liliana),Sco... Immunol Rev 2008-11-03

...SOCS3 to negatively regulate activation and/or differentiation pathways in macrophages, dendritic cells, and T lymphocyt...

Elevated expression and polymorphisms of SOCS3 influence patient response to ...

Persico(M),Capasso(M),Russo(R),Persico(E),... Gut 2008-03-28

...SOCS3) in 162 NR and 184 SVR subjects (SOCS3 -8464 A/C (rs12952093), -4874 A/G (rs4969170) and 1383 A/G, (rs4969168)).,S...

Evaluation of candidate methylation markers to detect cervical neoplasia.

Shivapurkar(Narayan),Sherman(Mark E),Stast... Gynecol Oncol 2008-01-07

...SOCS3, HS3ST2 and CDH1) previously demonstrated as methylated in cervical cancer.,In this analysis, we performed methyla...

Association of serum and follicular fluid leptin concentrations with granulos...

Li(Mei-Gen),Ding(Guo-Lian),Chen(Xi-Jing),L... J Clin Endocrinol Metab 2008-02-07

...SOCS3) system in the ovary.,A case-control study was conducted in a university hospital.,Thirty-one infertile PCOS women...

Sequential activation of JAKs, STATs and xanthine dehydrogenase/oxidase by hy...

Wang(Guansong),Qian(Pin),Jackson(Fannie R)... Int J Biochem Cell Biol 2008-05-30

...SOCS3), implying that hypoxia-promoted IL6 secretion activates the JAK/STAT pathway in LMVEC. Phosphorylation and DNA-bi...

SOCS3 promotes TLR4 response in macrophages by feedback inhibiting TGF-beta1/...

Liu(Xia),Zhang(Yongliang),Yu(Yizhi),Yang(X... Mol Immunol 2008-05-22

...SOCS3) has been shown to be induced by TGF-beta1 in osteoclast/macrophage, while the reports on the role of SOCS3 in reg...

Effect of ovariectomy on cardiac gene expression: inflammation and changes in...

Hamilton(Karyn L),Lin(Li),Wang(Yin),Knowlt... Physiol Genomics 2008-06-16

...SOCS3 mRNA, SOCS2 and SOCS3 protein did not differ among groups. In light of these findings, investigation into the net ...

Generation of T cell regulatory activity by plasmacytoid dendritic cells and ...

Puccetti(Paolo),Fallarino(Francesca) Blood Cells Mol Dis 2008-02-26

...SOCS3). In addition, engagement of GITR ligand by GITR-Ig in pDCs also resulted in IDO activity via type I IFNs and nonc...

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