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Overexpression of suppressor of cytokine signaling-3 in T cells exacerbates a...

Numata(Kosuke),Kubo(Masato),Watanabe(Hiroy... J Immunol 2007-05-22

...SOCS3 in T cells in APAP-induced liver injury. Mice with a cell-specific overexpression of SOCS3 in T cells (SOCS3Tg, in...

Susceptibility to asthma and eczema from mucosal and epidermal expression of ...

Jones(Graham) Curr Allergy Asthma Rep 2007-05-31

...SOCS3) that are involved in the activation of T-helper 2 cells, the microbial pattern recognition receptors nucleotide-b...

The SOCS box of suppressor of cytokine signaling-3 contributes to the control...

Boyle(Kristy),Egan(Paul),Rakar(Steven),Wil... Blood 2007-10-19

...SOCS3 protein lacking the C-terminal SOCS box (SOCS3(Delta SB/Delta SB)). SOCS3(Delta SB/Delta SB) mice were viable, had...

Suppressor of cytokine signaling 3 regulates CD8 T-cell proliferation by inhi...

Brender(Christine),Tannahill(Gillian M),Je... Blood 2007-11-06

...SOCS3 in T/natural killer T cells (Socs3(DeltaLck/DeltaLck) mice). SOCS3-deficient CD8 T cells showed greater proliferat...

Regulation of suppressor of cytokine signaling 3 (SOC3) by growth hormone in ...

Barclay(Johanna L),Anderson(Stephen T),Wat... Mol Endocrinol 2007-12-06

...SOCS3 expression. GH treatment of these cells caused a rapid, dose-dependent increase in SOCS3 mRNA expression, which wa...

Deficient SOCS3 expression in CD4+CD25+FoxP3+ regulatory T cells and SOCS3-me...

Pillemer(Brendan B L),Xu(Hui),Oriss(Timoth... Eur J Immunol 2007-09-21

...SOCS3 negatively regulates responses to IL-2 and IL-6. Interestingly, unlike Th cells, Treg were found to be deficient i...

STAT3 and suppressor of cytokine signaling 3: potential targets in lung infla...

Gao(Hongwei),Ward(Peter A) Expert Opin Ther Targets 2007-08-21

...SOCS3. Recently, data on the activation and function of STAT3 and SOCS3 in the lung during the acute inflammatory respon...

Methylation status of the SOCS3 gene in human malignant melanomas.

Tokita(Tomoko),Maesawa(Chihaya),Kimura(Tos... Int J Oncol 2007-03-29

...SOCS3 gene have not been elucidated. We therefore examined the methylation status and/or protein expression of the SOCS3...

The myeloproliferative disorder-associated JAK2 V617F mutant escapes negative...

Hookham(Michelle B),Elliott(Joanne),Suessm... Blood 2007-07-02

...SOCS3. Instead of acting as a suppressor, SOCS3 enhanced the proliferation of cells expressing both JAK2 V617F and EPOR....

Role of signal transducer and activator of transcription 3 in liver fibrosis ...

Stärkel(Peter),Saeger(Christine De),Lecler... Lab Invest 2007-04-05

...Socs3) in 65 HCV-infected livers at various stages of fibrosis progression. We then determined the level of expression o...

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