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Chronic tumor necrosis factor-alpha treatment causes insulin resistance via i...

Ishizuka(Ken),Usui(Isao),Kanatani(Yukiko),... Endocrinology 2007-07-24

...SOCS3 induction and signal transducer and activator of transcription-3 phosphorylation. These results suggest that SOCS3...

IFN-alpha-induced signal transduction, gene expression, and antitumor activit...

Zimmerer(Jason M),Lesinski(Gregory B),Kond... J Immunol 2007-05-21

...SOCS3 in Jurkat cells and normal T cells enhanced the transcriptional response to IFN-alpha. Loss of SOCS1 or SOCS3 in m...

Gene function in early mouse embryonic stem cell differentiation.

Hailesellasse Sene(Kagnew),Porter(Christop... BMC Genomics 2007-05-11

...Socs3, Tagln, Tdgf1), our analysis points to others (such as transcription factor Phf21a, extracellular matrix related L...

Expression of suppressor of cytokine signaling 3 (SOCS3) and cytokine-inducib...

Ekchariyawat(P),Pudla(S),Limposuwan(K),Arj... Microb Pathog 2007-05-25

...SOCS3) and cytokine-inducible Src homology 2-containing protein (CIS). In the present study, we presented evidence showi...

STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo.

Pietrangelo(Antonello),Dierssen(Uta),Valli... Gastroenterology 2007-03-14

...SOCS3) expression in livers of wild-type and alfpCregp130(Y757F/LoxP) mice, whereas this response was blocked in alfpCre...

Heat shock stress ameliorates cytokine mixture-induced permeability by downre...

Wang(Quan),Guo(Xia-Ling),Noel(Greg),Ogle(C... Shock 2007-04-05

...SOCS3. The SA treatment also decreased cytomix-induced IL-6 and IL-8 production in a dose-dependent manner. In conclusio...

Pancreatitis-associated protein: from a lectin to an anti-inflammatory cytokine.

Closa(Daniel),Motoo(Yoshiharu),Iovanna(Jua... World J Gastroenterol 2007-03-09

...SOCS3 through the JAK/STAT3-dependent pathway. The JAK/STAT3/SOCS3 pathway seems to be a common point between PAP and se...

IL-18 time-dependently modulates Th1/Th2 cytokine production by ligand-activa...

Uchida(Takefumi),Kinoshita(Manabu),Fukasaw... Eur J Immunol 2007-05-25

...SOCS3 was notably up-regulated in the liver MNC from mice pretreated 6 h before with IL-18; in particular, SOCS3 express...

Effects of pioglitazone on suppressor of cytokine signaling 3 expression: pot...

Kanatani(Yukiko),Usui(Isao),Ishizuka(Ken),... Diabetes 2007-04-26

...SOCS3 mRNA in fat tissue was increased compared with that in lean control mice, and pioglitazone suppressed SOCS3 levels...

A novel c-Jun-dependent signal transduction pathway necessary for the transcr...

Gough(Daniel J),Sabapathy(Kanaga),Ko(Enoch... J Biol Chem 2007-03-07

...SOCS3, were unaffected, and chromatin immunoprecipitation demonstrated that c-Jun binds to the iNOS promoter following t...

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