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Lipopolysaccharide pretreatment modulates the disease course in experimental ...

Buenafe(Abigail C),Bourdette(Dennis N) J Neuroimmunol 2007-03-09

...SOCS3 in the LPS pre-treated mice. Thus, exposure to LPS prior to EAE induction affects antigen presentation and may mod...

Attenuation of leptin and insulin signaling by SOCS proteins.

Howard(Jane K),Flier(Jeffrey S) Trends Endocrinol Metab 2007-02-01

...SOCS3 appears to be of particular importance in the development of leptin resistance, whereas the ability to diminish in...

CD33 responses are blocked by SOCS3 through accelerated proteasomal-mediated ...

Orr(Selinda J),Morgan(Nuala M),Elliott(Joa... Blood 2007-03-06

...SOCS3 can specifically bind to the phosphorylated ITIM of CD33. Additionally, following cross-linking SOCS3 can recruit ...

Impaired downregulation following erythropoietin receptor activation in non-s...

Dunlop(Elaine A),Maxwell(Alexander P),Lapp... Stem Cells 2007-03-15

...SOCS3 induction downstream of erythropoietin stimulation and an extremely delayed SOCS1 response. If this finding in non...

Conditional mutagenesis reveals immunological functions of widely expressed g...

Roes(J) Handb Exp Pharmacol 2007-01-17

...Socs3, for example, established their key role in the prevention of inappropriate inflammation, while unexpected immunor...

SOCS3 is required to temporally fine-tune photoreceptor cell differentiation.

Ozawa(Yoko),Nakao(Keiko),Shimazaki(Takuya)... Dev Biol 2007-04-26

...SOCS3 mRNA level was constant from the late-embryonic to early-postnatal period. Post-transcriptional inhibition of SOCS...

Socs 3 modulates the activity of the transcription factor Stat3 in mammary ti...

Robinson(Gertraud W),Pacher-Zavisin(Margit... Dev Dyn 2007-08-01

...Socs3) has been implicated in the modulation of both Stat3 and Stat5 activity. To explore the biology of Socs3 in mammar...

STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo.

Pietrangelo(Antonello),Dierssen(Uta),Valli... Gastroenterology 2007-03-14

...SOCS3) expression in livers of wild-type and alfpCregp130(Y757F/LoxP) mice, whereas this response was blocked in alfpCre...

Molecular mechanisms involved in interleukin-4-induced human neutrophils: exp...

Ratthé(Claude),Pelletier(Martin),Chiasson(... J Leukoc Biol 2007-11-09

...SOCS3 at the mRNA and protein levels. The effect of IL-4 on SOCS3 protein expression was increased markedly when the pro...

Expression of suppressor of cytokine signaling 3 (SOCS3) and cytokine-inducib...

Ekchariyawat(P),Pudla(S),Limposuwan(K),Arj... Microb Pathog 2007-05-25

...SOCS3) and cytokine-inducible Src homology 2-containing protein (CIS). In the present study, we presented evidence showi...

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