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Cathepsin-L contributes to cardiac repair and remodelling post-infarction.

Sun(Mei),Chen(Manyin),Liu(Youan),Fukuoka(M... Cardiovasc Res 2011-04-22

...CTSL-deficient (Ctsl(-/-)) mice (B6 × FSB/GnEi a/a Ctsl(fs)/J) and wild-type littermates (Ctsl(+/+)) by left coronary ar...

Roles for cathepsins S, L, and B in insulitis and diabetes in the NOD mouse.

Hsing(Lianne C),Kirk(Elizabeth A),McMillen... J Autoimmun 2010-06-14

...Ctsl-/-) are completely protected from IDDM, as originally shown by others. Ctsl, Ctss, or Ctsb heterozygous mice were a...

The cystatin M/E-cathepsin L balance is essential for tissue homeostasis in e...

Zeeuwen(Patrick L J M),van Vlijmen-Willems... FASEB J 2010-11-01

...Ctsl(-/-) and Cst6(-/-)Ctsl(+/-) mice were viable, but the absence of cystatin M/E caused scarring alopecia in adult ani...

Association between cathepsin L (CTSL) and cathepsin S (CTSS) polymorphisms a...

Fontanesi(L),Speroni(C),Buttazzoni(L),Scot... Meat Sci 2010-07-14

...CTSL and CTSS genes identified two new single nucleotide polymorphisms (SNPs), one located in exon 5 (CTSL) and one posi...

Activation and repression domains within the promoter of the rat cathepsin L ...

Visone(Thomas),Charron(Martin),Wright(Will... Biol Reprod 2010-01-05

In murine testes, only Sertoli cells express the cathepsin L (Ctsl) gene, and this expression is restricted to stages V-...

Deficiency for the cysteine protease cathepsin L promotes tumor progression i...

Dennemärker(J),Lohmüller(T),Mayerle(J),Tac... Oncogene 2010-04-23

...Ctsl) during squamous carcinogenesis, we generated mice harboring a constitutive Ctsl deficiency in addition to epitheli...

The cathepsin L gene is a direct target of FOXO1 in skeletal muscle.

Yamazaki(Yoshihiro),Kamei(Yasutomi),Sugita... Biochem J 2010-04-15

...Ctsl and human CTSL1 promoters. The luciferase reporter analysis revealed that the mouse Ctsl and human CTSL1 promoters ...

Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduc...

Wartmann(Thomas),Mayerle(Julia),Kähne(Thil... Gastroenterology 2010-04-01

...CTSL) can also process trypsinogen to active trypsin and has a role in pancreatitis.,In CTSL-deficient (Ctsl(-/-)) mice,...

Truncated human cathepsin L, encoded by a novel splice variant, exhibits alte...

Sansanwal(Poonam),Shukla(Abhay A),Das(Tapo... Protein Pept Lett 2010-07-01

...ctsl, upon over expression in eukaryotic cells Deltactsl is not secreted in to the media. Immunogold electron microscopy...

A new chitosan biopolymer derivative as metal-complexing agent: synthesis, ch...

Krishnapriya(K R),Kandaswamy(M) Carbohydr Res 2010-12-30

In this study, a new chitosan biopolymer derivative (CTSL) has been synthesized by anchoring a new vanillin-based comple...

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