Claiborn(Kathryn C),Sachdeva(Mira M),Cannon(… J Clin Invest 2010-11-10

...SPOP) is a nuclear protein that inhibits Pdx1 transactivation. Here, we show that Pcif1 targets Pdx1 for ubiquitination ...

Liu(Jiang),Ghanim(Murad),Xue(Lei),Brown(Chri… Science 2009-03-09

...SPOP. In Drosophila, the gene encoding SPOP is a target of segmentation transcription factors. Drosophila SPOP mediates ...

Ruel(Laurent),Thérond(Pascal P) Genes Dev 2009-08-28

...Spop in a cilia-independent manner.

Chen(Miao-Hsueh),Wilson(Christopher W),Li(Ya… Genes Dev 2009-08-28

...Spop, a conserved Gli-degrading factor. Furthermore, addition of zebrafish or fly Sufu restores Gli protein function in ...

Zhuang(Min),Calabrese(Matthew F),Liu(Jiang),… Mol Cell 2009-12-21

...SPOP. We define a SPOP-binding consensus (SBC) and determine structures revealing recognition of SBCs from the phosphata...

Byun(Boohyeong),Tak(Heejae),Joe(Cheol O) Biofactors 2009-01-12

...SPOP. Studies using SPOP deletion mutants suggest that BTB/POZ domain of SPOP protein is important for the induction of ...

Bunce(Matthew W),Boronenkov(Igor V),Anderson… J Biol Chem 2008-05-20

...SPOP interact and co-localize at nuclear speckles in mammalian cells, and SPOP mediates the ubiquitylation of PIPKIIbeta...

Byun(Boohyeong),Jung(Yunhwa) Mol Cells 2008-08-04

...SPOP containing the MATH domain interacts with the AF-2 domain of ER alpha in cultured human embryonic 293 cells. SPOP w...

Di Marcotullio(Lucia),Ferretti(Elisabetta),G… Cell Cycle 2007-04-12

...SPOP-dependent proteolytic processing or degradation of Drosophila Cubitus interruptus or mammalian Gli proteins. We hav...

Zhang(Qing),Zhang(Lei),Wang(Bing),Ou(Chan-Ye… Dev Cell 2006-07-19

...SPOP, can functionally substitute for HIB, and Gli proteins are degraded by HIB/SPOP in Drosophila. We provide evidence ...