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Innate defense mechanism against virus infection within the cardiac myocyte r...

Yajima(Toshitaka),Yasukawa(Hideo),Jeon(Eun... Circulation 2007-01-23

...SOCS3 transgenic and gp130-deficient mice had a decrease in alpha-sarcoglycan.,SOCS3-mediated regulation of gp130 signal...

Rofecoxib modulates multiple gene expression pathways in a clinical model of ...

Wang(Xiao-Min),Wu(Tian-Xia),Hamza(May),Ram... Pain 2007-03-19

...SOCS3 (suppressor of cytokine signaling 3) and IL1RN (IL1 receptor antagonist) which are associated with inhibition of p...

Increased SOCS6 stability with PMA requires its N-terminal region and the Erk...

Hwang(Mi-Na),Ha(Tae Hun),Park(Jongsun),Shi... Biochem Biophys Res Commun 2007-04-06

...SOCS3 or Erk1 with PMA. This result suggests that the increased stability of SOCS6 with PMA did not generally occur in o...

Altered expression of SOCS3 in the hypothalamic arcuate nucleus during season...

Król(E),Tups(A),Archer(Z A),Ross(A W),Moar... J Neuroendocrinol 2007-03-29

...SOCS3). We used in situ hybridisation to examine hypothalamic arcuate nucleus (ARC) expression of SOCS3, neuropeptide Y ...

STAT3 signaling is activated in human skeletal muscle following acute resista...

Trenerry(Marissa K),Carey(Kate A),Ward(Ali... J Appl Physiol (1985) 2007-05-22

...SOCS3 (60-fold). Thus, following a single bout of intense resistance exercise, a rapid phosphorylation and nuclear trans...

Suppressor of cytokine signalling-3 at pathological levels does not regulate ...

Prêle(Cecilia M),Keith-Magee(April L),Yerk... Immunology 2007-10-24

...SOCS3 in LPS-induced and IL-10-mediated suppression of TNF-alpha production by non-transformed human monocytes. SOCS3 ov...

Activin A inhibits organization of sarcomeric proteins in cardiomyocytes indu...

Florholmen(G),Halvorsen(B),Beraki(K),Lyber... J Mol Cell Cardiol 2007-01-12

...SOCS3 gene expression, while LIF potently increased the expression of Smad7 mRNA, representing inhibitors of LIF and act...

STAT3 governs distinct pathways in emergency granulopoiesis and mature neutro...

Panopoulos(Athanasia D),Zhang(Ling),Snow(J... Blood 2007-01-04

...Socs3, which encodes a crucial feedback inhibitor of cytokine signaling. Our results demonstrate the existence of distin...

IFN-gamma-induced BACE1 expression is mediated by activation of JAK2 and ERK1...

Cho(Hyun Jin),Kim(Su-Kyoung),Jin(Seok Min)... Glia 2007-03-16

...SOCS3 expression suppressed BACE1 promoter by blocking phosphorylation of Tyr701 residue in STAT1. Also, because IFN-gam...

Loss of SOCS3 gene expression converts STAT3 function from anti-apoptotic to ...

Lu(Yang),Fukuyama(Satoru),Yoshida(Ryoko),K... J Biol Chem 2007-01-30

...SOCS3(-/-) MEFs but not in wild-type MEFs, and Akt/protein kinase B activity was substantially reduced in SOCS3(-/-) MEF...

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