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Circulating hormones and hypothalamic energy balance: regulatory gene express...

Mitchell(Sharon E),Nogueiras(Ruben),Rance(... J Endocrinol 2006-12-18

...SOCS3) gene expression in response to leptin challenge were compared with Wistar rats. Plasma leptin levels were lower i...

Structural basis for phosphotyrosine recognition by suppressor of cytokine si...

Bergamin(Elisa),Wu(Jinhua),Hubbard(Stevan ... Structure 2006-10-24

...SOCS3 includes the so-called kinase inhibitory region that has been shown to inhibit the catalytic activity of JAK2. Her...

Overexpression of SOCS3 is associated with decreased survival in a cohort of ...

Krishnadasan(Ravitharan),Bifulco(Carlo),Ki... Br J Haematol 2006-11-06

...SOCS3-positive (n = 42) or -negative (n = 40) cohorts, and overall survival (OS) was analysed. SOCS3-positive FL patient...

Suppressor of cytokine signaling-3 suppresses the ability of activated signal...

Miao(Tizong),Wu(Dongsheng),Zhang(Yi),Bo(Xu... J Neurosci 2006-10-20

...SOCS3, or a mutant SOCS3 with dominant-negative actions. The SOCS3 construct was effective in inhibiting tyrosine phosph...

Interleukin-10 anti-inflammatory response to Borrelia burgdorferi, the agent ...

Dennis(Vida A),Jefferson(Ayanna),Singh(Shr... Infect Immun 2006-11-28

...SOCS3 mRNA and protein expression, with SOCS3 being more abundant. Pam(3)Cys, a synthetic lipopeptide, also induced SOCS...

Interleukin 27 negatively regulates the development of interleukin 17-produci...

Stumhofer(Jason S),Laurence(Arian),Wilson(... Nat Immunol 2006-11-28

...SOCS3. Thus IL-27, a potent inhibitor of T(H)-17 cell development, may be a useful target for treating inflammatory dise...

Distinct impaired regulation of SOCS3 and long and short isoforms of the lept...

Séron(Karin),Corset(Laetitia),Vasseur(Fran... Biochem Biophys Res Commun 2006-10-19

...SOCS3 mRNA are detected at very low levels. Subcutaneous/visceral ratios for OB-Ra the short OB-R isoform, OB-Rb, and SO...

Common polymorphisms in SOCS3 are not associated with body weight, insulin se...

Jamshidi(Y),Snieder(H),Wang(X),Spector(T D... Diabetologia 2006-04-06

...SOCS3 (rs4969169, rs12953258 and rs8064821) and obesity measures, insulin sensitivity measures and serum lipids in the g...

STAT3 activation via interleukin 6 trans-signalling contributes to ileitis in...

Mitsuyama(K),Matsumoto(S),Rose-John(S),Suz... Gut 2006-09-21

...SOCS3 and interleukin 6 (IL-6) mRNA were determined by northern blotting and reverse transcription-polymerase chain reac...

Grasp a pTyr-peptide by its SOCS.

Hirano(Toshio),Murakami(Masaaki) Dev Cell 2006-06-12

...SOCS3 in complex with a phosphotyrosine-containing peptide from the IL-6 receptor subunit gp130, and they identified the...

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