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Mislocalization of the centromeric histone variant CenH3/CENP-A in human cell...

Lacoste(Nicolas),Woolfe(Adam),Tachiwana(Hi... Mol Cell 2014-04-22

...DAXX rather than the dedicated CenH3 chaperone HJURP. This aberrant nucleosome occludes CTCF binding and has a minor eff...

Death domain-associated protein 6 (Daxx) selectively represses IL-6 transcrip...

Yao(Zhenyu),Zhang(Qian),Li(Xia),Zhao(Dezhi... J Biol Chem 2014-05-21

...Daxx in innate immunity remains unclear. In our study, we show that Daxx is highly expressed in macrophages and localize...

Reversible silencing of cytomegalovirus genomes by type I interferon governs ...

Dağ(Franziska),Dölken(Lars),Holzki(Julia),... PLoS Pathog 2014-10-03

...Daxx, and their knockdown by shRNA rescued viral replication in the presence of IFNβ. Finally, IFNβ prevented MCMV react...

[Death domain-associated protein (DAXX)-mediated regulation of transcription ...

Muromoto(Ryuta) Yakugaku Zasshi 2014-02-28

...DAXX) is a multifunctional protein that modulates both cell death and transcription. DAXX predominantly localizes in the...

The 19S proteasome activator promotes human cytomegalovirus immediate early g...

Winkler(Laura L),Kalejta(Robert F) J Virol 2014-11-25

...Daxx, a cellular transcriptional repressor that can silence viral immediate early (IE) gene expression. We previously sh...

Dengue virus disrupts Daxx and NF-κB interaction to induce CD137-mediated apo...

Netsawang(Janjuree),Panaampon(Jutatip),Khu... Biochem Biophys Res Commun 2014-11-04

...Daxx to disrupt interaction between Daxx and NF-κB. The liberated NF-κB activated the promoter of CD137, which is a memb...

The PML domain of PML-RARα blocks senescence to promote leukemia.

Korf(Katharina),Wodrich(Harald),Haschke(Al... Proc Natl Acad Sci U S A 2014-11-03

...Daxx-histone H3.3 predisposition complex and suggests inhibition of senescence as a targetable mechanism in APL therapy....

Activation of extrinsic- and Daxx-mediated pathways in lymphoid tissue of PRR...

Rodríguez-Gómez(Irene M),Barranco(Inmacula... Vet Microbiol 2014-10-24

...Daxx, CCasp3 and PRRSV expression were analyzed by immunohistochemistry. An up-regulation of CCasp8, Fas and CCasp3 expr...

Molecular genetics of pancreatic neoplasms and their morphologic correlates: ...

Reid(Michelle D),Saka(Burcu),Balci(Serdar)... Am J Clin Pathol 2014-03-04

...DAXX/ATRX is only seen in pancreatic neuroendocrine tumors, making it a useful potential marker in distinguishing these ...

Neuroendocrine tumors of the pancreas: current concepts and controversies.

Reid(Michelle D),Balci(Serdar),Saka(Burcu)... Endocr Pathol 2014-12-18

...DAXX and ATRX proteins has been recently identified in 45 %. Along with these improvements, several controversies remain...

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