...SLC26A3, previously known as CLD or DRA) are responsible for the disease. Since the identification of the SLC26A3 gene a...
...SLC26A3), previously known as CLD or DRA (downregulated in adenomas). To date, almost 30 different mutations in the SLC2...
...SLC26A3), which disrupt epithelial Cl(-) /HCO3 (-) transport in the ileum and colon. Although 55 mutations in SLC26A3 ha...
...Slc26a3 genes were upregulated 3.7- to 30.2-fold in tumors with mutant Kras.,These results demonstrated the validity of ...
...SLC26A3 gene that encodes the protein regulating chloride bicarbonate absorption in distal ileum and colon. Therapy with...
SLC26A3 or Downregulated in adenoma (DRA) is the major Cl(-)/HCO3 (-) exchanger involved in electroneutral NaCl absorpti...
...SLC26A3) was confirmed. With the combined use of proteomic and genetic tools, it was reported, for the first time to the...
...SLC26A3 as a tumour suppressor is restricted to colon; it is a Cl(-)/HCO(-) 3 exchanger, facilitating the efflux of HCO(...
...Slc26a3 (DRA)-mediated luminal Cl(-)/HCO3 (-) exchange or PEPT1-mediated H(+)/dipeptide uptake. Possibly because of the ...
...SLC26A3 (DRA) (Cl(-)/HCO3 (-)) that control intestinal fluid transport. We hypothesized that enterocyte maturation defec...
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