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The effects of suppressor of cytokine signalling 3 in glucose intolerance of ...

Qin(G),Deng(K),Pan(M),Huang(D),Li(X),Liu(Y... Br J Nutr 2026-01-16

...SOCS3 encoded 225 amino acids, including conserved domains SH2 and SOCS3-box. The SOCS3 was knocked down by specific siR...

Machine learning based prioritisation of genes associated with osteoarthritis...

Soul(J),Young(DA) Osteoarthritis Cartilage 2026-03-00

...SOCS3, and NFKBIA. Incorporation of OpenTargets druggability data highlighted putative clinically tractable genes for fu...

Epigenome-wide association study of circulating interleukin-6 connects DNA me...

Sinke(L),van Dongen(J),Delerue(T),Wilson(R... Commun Biol 2026-02-04

...SOCS3 (Suppressor of Cytokine Signalling 3) methylation statistically mediating inflammatory bowel disease risk. Notably...

Suppressor of cytokine signaling (SOCS) proteins in human retroviral infections.

Farjami(Z),Akbarin(MM),Álvarez(HR) Mol Biol Rep 2026-02-05

...SOCS3 to dampen antiviral interferon signaling, inhibit STAT activation, impair antigen presentation, and promote viral ...

Molecular mechanism of berberine in ameliorating leptin resistance and mitoch...

Zhang(X),Zhang(C),Meng(X),Tang(J) Chin Med 2026-01-26

...SOCS3 expression. Meanwhile, TRIB1 appears to mediate the remodeling of mitochondrial dynamics by increasing the express...

A mechanistic axis of shear stress, reactive oxygen species, and microRNAs un...

Nair(PS),Banerjee(S),Mahapatra(NR),Suraish... Mol Biol Rep 2026-01-03

...SOCS3, and CEBPB as key miRNA targets linked to MI. Experimental validation confirmed shear-associated ROS generation, d...

Mesenchymal stromal cells alleviate pulmonary arterial hypertension by suppre...

Wang(J),Jin(J),Zhang(M),Chen(X),Du(S),Mao(... Stem Cell Res Ther 2026-01-05

...SOCS3 and consequent inhibition of STAT3 phosphorylation. Our findings underscore the importance of early intervention i...

Locally constrained xylene-based cyclic mimetics of SOCS3 protein.

Cugudda(A),La Manna(S),Cozzolino(F),Tolbat... Eur J Med Chem 2026-01-05

The development of SOCS3 peptidomimetics targeting the JAK2 signaling pathway presents a promising strategy for modulati...

Gain-of-Function Variant in STAT3 and Retinal Macular Edema: Insights into th...

Zhou(Z),Lourens(MS),Meesilpavikkai(K),Miss... Ocul Immunol Inflamm 2026-01-00

...SOCS3 overexpression in STAT3 GOF RPE cells. The pathogenic STAT3 p.L387R GOF variant enhances inflammatory cytokine pro...

Uncovering Allele-Specific Expression Patterns Associated with Sea Lice (Cali...

Cáceres(P),López(P),Araya(C),Cichero(D),Ba... Genes (Basel) 2025-07-19

...SOCS3, CSF3R, and Neutrophil cytosolic factor suggest individual variation in cytokine signaling and oxidative stress pa...

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