Lane(B Josh),Mutchler(Charla),Al Khodor(Souh… PLoS Pathog 2008-04-28

...Vav2, in a phosphotyrosine-dependent manner. The tyrosine phosphorylation profile of the sequence YEPISTENIYESI within T...

Takahashi(Motonori),Rikitake(Yoshiyuki),Naga… Genes Cells 2008-07-16

...Vav2 and PAK at peripheral ruffles, which was inhibited by Rap1GAP and knockdown of Rap1. These results indicate that Ra...

Itoh(Reina E),Kiyokawa(Etsuko),Aoki(Kazuhiro… J Cell Sci 2008-11-04

...Vav2 have been shown to transduce the growth signal from the EGF receptor to Rac1. To clarify the role of each GEF, we t...

Lee(Li-Fen),Lih(Chih-Jian),Huang(Chao-Jen),C… Proc Natl Acad Sci U S A 2008-08-19

...Vav2, Rho GTPase-activating protein, calcium channel voltage-dependent, L type alpha1C subunit (CaV1.2), IL-1 receptor-a...

Molli(Poonam R),Adam(Liana),Kumar(Rakesh) Clin Cancer Res 2008-11-26

...Vav2 guanine nucleotide exchange factor and activation of RhoA GTPase irrespective of EGFR level, and Vav2 interacted wi...

Arora(P D),Marignani(P A),McCulloch(C A) Am J Physiol Cell Physiol 2008-10-01

...Vav2, which correlated temporally with increased Rac1 activity. Knockdown of Vav2 prevented Rac activation, recruitment ...

Fang(Wei Bin),Brantley-Sieders(Dana M),Hwang… J Biol Chem 2008-07-15

...Vav2 and Vav3 guanine nucleotide exchange factors, whereas Tyr(P)(734) binds to the p85 regulatory subunit of phosphatid...

Birukova(Anna A),Zagranichnaya(Tatiana),Fu(P… Exp Cell Res 2007-08-17

...Vav2-dependent pathways of Rac1 activation and EC barrier regulation. Knockdown of Epac, Rap1, Rac-specific exchange fac...

Weckbecker(Gisbert),Bruns(Christian),Fischer… Transpl Int 2007-04-27

...Vav2-ko mice (n = 5) was >100 and >77 days, compared with 8-9 days in the corresponding wild-type mice. Vav1/Vav2-ko mic...

Yi(Fan),Chen(Qi-Zheng),Jin(Si),Li(Pin-Lan) Cell Physiol Biochem 2007-12-19

...Vav2 was found to be a predominant isoform among Vav family in RMCs. In Vav2-siRNA transfected RMCs, Hcys-induced Rac ac...