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Defective Jak-Stat activation in hepatoma cells is associated with hepatitis ...

Zhu(Haizhen),Nelson(David R),Crawford(Jame... J Interferon Cytokine Res 2005-10-31

...SOCS3) expression in response to IFN stimulation, and blocking SOCS3 in the IFN-resistant cell line partially restores I...

Induction of keratinocyte migration via transactivation of the epidermal grow...

Tokumaru(Sho),Sayama(Koji),Shirakata(Yuji)... J Immunol 2005-11-28

...SOCS3/CIS3 almost completely abolished LL-37-induced keratinocyte migration. In conclusion, LL-37 induces keratinocyte m...

The control of allergic conjunctivitis by suppressor of cytokine signaling (S...

Ozaki(Akemi),Seki(Yoh-ichi),Fukushima(Atsu... J Immunol 2005-12-13

...SOCS3 was highly expressed at the disease site, and T cell-specific expression of SOCS3 deteriorated clinical and pathol...

Altered expression of immune defense genes in pilocytic astrocytomas.

Huang(Hervé),Hara(Akira),Homma(Taku),Yonek... J Neuropathol Exp Neurol 2005-11-03

...SOCS3 and those expressed at lower levels include EGFR and PDGFRA. Hierarchical clustering analysis using the entire set...

SOCS2 can enhance interleukin-2 (IL-2) and IL-3 signaling by accelerating SOC...

Tannahill(Gillian M),Elliott(Joanne),Barry... Mol Cell Biol 2005-11-21

...SOCS3 is enhanced by coexpression of elongin B/C. This suggests that SOCS2 can bind to SOCS3 and elongin B/C to form an ...

Deficient Stat3 DNA-binding is associated with high Pias3 expression and a po...

Stärkel(Peter),De Saeger(Christine),Lecler... J Hepatol 2005-11-28

...Socs3 levels. Bcl-2 was up-regulated in HCV and ALD together with decreased Caspase3 activity. Compared to base-line cel...

Burkholderia pseudomallei-induced expression of suppressor of cytokine signal...

Ekchariyawat(P),Pudla(S),Limposuwan(K),Arj... Infect Immun 2005-12-06

...SOCS3) and cytokine-inducible Src homology 2-containing protein (CIS) but not SOCS1 in a mouse macrophage cell line (RAW...

Mutation analysis of suppressor of cytokine signalling 3, a candidate gene in...

Gylvin(T),Nolsøe(R),Hansen(T),Nielsen(E M ... Diabetologia 2005-03-07

...SOCS3 could therefore be a candidate gene in the development of Type 1 and Type 2 diabetes mellitus.,Mutation analysis o...

[Regulation of cytokine and toll-like receptor signaling by SOCS family genes...

Takagi(Hiromi),Sanada(Takahito),Minoda(Yas... Nihon Rinsho 2005-01-28

...SOCS3 can inhibit JAK tyrosine kinase activity. We demonstrate that SOCS1 and SOCS3 play an important regulatory role in...

Increased mRNA expression of Th1-cytokine signaling molecules in patients wit...

Nishiura(Yoshihiro),Nakamura(Tatsufumi),Fu... Tohoku J Exp Med 2005-08-31

...SOCS3, a marker for Th2 cells, was significantly decreased in HTLV-I-infected individuals. These results indicate that H...

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