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IFN-gamma suppresses STAT6 phosphorylation by inhibiting its recruitment to t...

Huang(Zan),Xin(Junping),Coleman(John),Huan... J Immunol 2005-03-15

...SOCS3, or SOCS5 was observed in the two cell types. In addition, Src homology 2-containing phosphatase mutation did not ...

Modulation of the interleukin-6 receptor subunit glycoprotein 130 complex and...

Novotny-Diermayr(Veronica),Lin(Baohong),Gu... J Biol Chem 2005-05-13

...SOCS3). The binding domains involved in these interactions were mapped, and the interactions were shown to be in a direc...

Interleukin-22 activates STAT3 and induces IL-10 by colon epithelial cells.

Nagalakshmi(Marehalli L),Rascle(Anne),Zura... Int Immunopharmacol 2005-05-19

...SOCS3), a STAT3-responsive gene. Further analyses, by real time quantitative PCR, on a panel of chemokines and immune fu...

Genetic reduction of embryonic leukemia-inhibitory factor production rescues ...

Robb(Lorraine),Boyle(Kristy),Rakar(Steven)... Proc Natl Acad Sci U S A 2005-12-12

...SOCS3 die at midgestation because of placental failure, and SOCS3 ablation in a cell-type-specific manner results in cha...

SOCS2 can enhance interleukin-2 (IL-2) and IL-3 signaling by accelerating SOC...

Tannahill(Gillian M),Elliott(Joanne),Barry... Mol Cell Biol 2005-11-21

...SOCS3 is enhanced by coexpression of elongin B/C. This suggests that SOCS2 can bind to SOCS3 and elongin B/C to form an ...

The control of allergic conjunctivitis by suppressor of cytokine signaling (S...

Ozaki(Akemi),Seki(Yoh-ichi),Fukushima(Atsu... J Immunol 2005-12-13

...SOCS3 was highly expressed at the disease site, and T cell-specific expression of SOCS3 deteriorated clinical and pathol...

Altered expression of immune defense genes in pilocytic astrocytomas.

Huang(Hervé),Hara(Akira),Homma(Taku),Yonek... J Neuropathol Exp Neurol 2005-11-03

...SOCS3 and those expressed at lower levels include EGFR and PDGFRA. Hierarchical clustering analysis using the entire set...

Burkholderia pseudomallei-induced expression of suppressor of cytokine signal...

Ekchariyawat(P),Pudla(S),Limposuwan(K),Arj... Infect Immun 2005-12-06

...SOCS3) and cytokine-inducible Src homology 2-containing protein (CIS) but not SOCS1 in a mouse macrophage cell line (RAW...

Deficient Stat3 DNA-binding is associated with high Pias3 expression and a po...

Stärkel(Peter),De Saeger(Christine),Lecler... J Hepatol 2005-11-28

...Socs3 levels. Bcl-2 was up-regulated in HCV and ALD together with decreased Caspase3 activity. Compared to base-line cel...

Cutting edge: silencing suppressor of cytokine signaling 3 expression in dend...

Orabona(Ciriana),Belladonna(Maria Laura),V... J Immunol 2005-08-08

...SOCS3) in DCs by RNA interference renders CD28-Ig capable of activating IDO, likely as a result of unrestrained IFN-gamm...

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