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Modulation of the interleukin-6 receptor subunit glycoprotein 130 complex and...

Novotny-Diermayr(Veronica),Lin(Baohong),Gu... J Biol Chem 2005-05-13

...SOCS3). The binding domains involved in these interactions were mapped, and the interactions were shown to be in a direc...

IFN-gamma suppresses STAT6 phosphorylation by inhibiting its recruitment to t...

Huang(Zan),Xin(Junping),Coleman(John),Huan... J Immunol 2005-03-15

...SOCS3, or SOCS5 was observed in the two cell types. In addition, Src homology 2-containing phosphatase mutation did not ...

Roles of Stat3 and ERK in G-CSF signaling.

Kamezaki(Kenjirou),Shimoda(Kazuya),Numata(... Stem Cells 2005-09-27

...SOCS3, a negative regulator of granulopoiesis, were observed, and SOCS3 expression was not induced by G-CSF stimulation....

SOCS3/CIS3 negative regulation of STAT3 in HGF-induced keratinocyte migration...

Tokumaru(Sho),Sayama(Koji),Yamasaki(Kenshi... Biochem Biophys Res Commun 2005-03-11

...SOCS3/CIS3 by sixfold within 1h, but had minimum effect on SOCS1/JAB expression. Transfection with SOCS3/CIS3 almost com...

Anti-inflammatory roles of retinoic acid in rat brain astrocytes: Suppression...

Choi(Woo-Hyuck),Ji(Kyung-Ae),Jeon(Sae-Bom)... Biochem Biophys Res Commun 2005-04-13

...SOCS3 mRNA expression. These results suggest that RA induces an anti-inflammatory effect by suppressing the activation o...

The tyrosine 974 within the LIF-R-chain of the gp130/LIF-R heteromeric recept...

Clahsen(Thomas),Lehmann(Ute),Stross(Claudi... Cell Signal 2005-05-26

...SOCS3 and the protein tyrosine phosphatase SHP2. Signalling of leukaemia inhibitory factor (LIF), ciliary neurotrophic f...

Bcl-2 overexpression leads to increases in suppressor of cytokine signaling-3...

Vanasse(Gary J),Winn(Robert K),Rodov(Sofya... Mol Cancer Res 2005-03-31

...SOCS3 protein, suggesting a Bcl-2-associated mechanism underlying SOCS3 induction. Immunohistochemistry with SOCS3 antis...

Tumour necrosis factor alpha (TNF)-TNF receptor 1-inducible cytoprotective pr...

Sass(Gabriele),Shembade(Noula D),Tiegs(Gis... Biochem J 2005-06-27

...SOCS3, protected isolated primary mouse hepatocytes from TNF-induced apoptosis. The identification of protective genes i...

Upregulated production of IL-6, but not IL-10, by interferon-alpha induces SO...

Usui(Eiji),Nishii(Kazuhiro),Katayama(Naoyu... Hematol J 2005-04-11

...SOCS3 expression. Although upregulation of SOCS3 was also observed in the presence of IFN-alpha alone in IL-6-expressing...

Regulation of the immune system by SOCS family adaptor proteins.

Ilangumaran(Subburaj),Ramanathan(Sheela),R... Semin Immunol 2005-04-28

...SOCS3 in lymphocyte development and homeostasis, and in the regulation of macrophage and dendritic cell functions. In th...

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