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Identification of CCR2, flotillin, and gp49B genes as new G-CSF targets durin...

Iida(Satoshi),Kohro(Takahide),Kodama(Tatsu... J Leukoc Biol 2005-10-06

...SOCS3), JunB, and p19(INK4D), we newly identified several G-CSF targets, including genes for the CC chemokine receptor-2...

Interleukin-6 plays a crucial role in the hepatic expression of SOCS3 during ...

Yang(Xiang-Ping),Schaper(Fred),Teubner(And... J Hepatol 2005-11-28

...SOCS3: SOCS3 can be induced by other mediators in vitro, and it does not exclusively inhibit IL-6 signaling. The individ...

Leptin inhibits hypothalamic Npy and Agrp gene expression via a mechanism tha...

Morrison(Christopher D),Morton(Gregory J),... Am J Physiol Endocrinol Met... 2005-12-21

...Socs3) mRNA, was not significantly attenuated by ICV LY pretreatment. Because NPY/AgRP neurons project to the hypothalam...

Heat shock protein 60 activates cytokine-associated negative regulator suppre...

Zanin-Zhorov(Alexandra),Tal(Guy),Shivtiel(... J Immunol 2005-08-31

...SOCS3, in turn, inhibits the downstream effects of stromal cell-derived-1alpha (CXCL12)-CXCR4 interaction in: 1) phospho...

Mechanisms of SOCS3 phosphorylation upon interleukin-6 stimulation. Contribut...

Sommer(Ulrike),Schmid(Christine),Sobota(Ra... J Biol Chem 2005-11-08

...SOCS3 phosphorylation does not require SOCS3 recruitment to phosphotyrosine (Tyr(P)) 759 of gp130, and the kinetics of S...

IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammat...

McLoughlin(Rachel M),Jenkins(Brendan J),Gr... Proc Natl Acad Sci U S A 2005-09-12

...SOCS3 binding, but presenting hyperactivation of STAT1/3, T cell recruitment and CCL5 expression was enhanced. Conversel...

RET/PTC-induced gene expression in thyroid PCCL3 cells reveals early activati...

Puxeddu(E),Knauf(J A),Sartor(M A),Mitsutak... Endocr Relat Cancer 2005-08-22

...Socs3, Nf1, Jak2, Cpg21, Dusp6, Socs1, Stat1, Stat3, Cish) and transcription (Nr4a1, Junb, Hfh1, Runx1, Foxe1). Genes co...

Mutation analysis of suppressor of cytokine signalling 3, a candidate gene in...

Gylvin(T),Nolsøe(R),Hansen(T),Nielsen(E M ... Diabetologia 2005-03-07

...SOCS3 could therefore be a candidate gene in the development of Type 1 and Type 2 diabetes mellitus.,Mutation analysis o...

SOCS3 is a critical physiological negative regulator of G-CSF signaling and e...

Croker(Ben A),Metcalf(Donald),Robb(Lorrain... Immunity 2004-03-31

To determine the importance of suppressor of cytokine signaling-3 (SOCS3) in the regulation of hematopoietic growth fact...

Leptin receptor signaling and the regulation of mammalian physiology.

Myers(Martin G) Recent Prog Horm Res 2004-04-29

...SOCS3), as well as important positive effectors of leptin action. The Jak2-dependent activation of the insulin receptor ...

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