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Involvement of casein kinase Iepsilon in cytokine-induced granulocytic differ...

Okamura(Atsuo),Iwata(Nobuko),Nagata(Aki),T... Blood 2004-05-27

...SOCS3) was stabilized by its physical association with CKIepsilon. Such stabilization by CKIepsilon was also seen in IL-...

Distinct activities of suppressor of cytokine signaling (SOCS) proteins and i...

van de Geijn(Gert-Jan M),Gits(Judith),Touw... J Leukoc Biol 2004-08-03

...SOCS3 expression was further elevated, while SOCS1 levels remained constant. SOCS box deletion mutants of SOCS1 and SOCS...

Endurance training partially reverses dietary-induced leptin resistance in ro...

Steinberg(Gregory R),Smith(Angela C),Worma... Am J Physiol Endocrinol Met... 2004-02-12

...SOCS3 expression. Future studies should examine changes in the actual protein content of SOCS3 in muscle and establish w...

Suppressor of cytokine signaling 6 associates with KIT and regulates KIT rece...

Bayle(Julie),Letard(Sébastien),Frank(Ronal... J Biol Chem 2004-05-07

...SOCS3 have been implicated in the down-regulation of cytokine signaling. The function of SOCS4, 5, 6, and 7 are not know...

SOCS3 is a physiological negative regulator for granulopoiesis and granulocyt...

Kimura(Akiko),Kinjyo(Ichiko),Matsumura(Yum... J Biol Chem 2004-04-30

...SOCS3(fl/fl) mice and Tie2-Cre:SOCS3(fl/fl) mice, in which the Socs3 gene had been deleted in mature neutrophils and hem...

Photoperiodic regulation of leptin sensitivity in the Siberian hamster, Phodo...

Tups(Alexander),Ellis(Claire),Moar(Kim M),... Endocrinology 2004-03-23

...SOCS3 mRNA to LD levels, whereas leptin treatment had no effect on SOCS3 gene expression in LD hamsters. Our results sug...

Suppressors of cytokine signaling and immunity.

Kubo(Masato),Hanada(Toshikatsu),Yoshimura(... Nat Immunol 2004-01-05

...SOCS3 regulate T cells as well as antigen-presenting cells, including macrophages and dendritic cells. Here we review th...

Differential activation of signal transducer and activator of transcription (...

Anderson(Per),Sundstedt(Anette),Li(Li),O'N... Int Immunol 2004-07-02

...SOCS3 was higher in T(h)1 cells. The differential induction of SOCS proteins was paralleled by the differential expressi...

TLR signaling at the intestinal epithelial interface.

Abreu(Maria T),Thomas(Lisa S),Arnold(Eliza... J Endotoxin Res 2004-05-05

...SOCS3. We conclude from our studies that the intestinal epithelium down-regulates expression of TLR4 and MD-2 and is LPS...

The role of the inhibitors of interleukin-6 signal transduction SHP2 and SOCS...

Fischer(Patrick),Lehmann(Ute),Sobota(Rados... Biochem J 2004-05-19

...SOCS3 (suppressor of cytokine signalling) are potent inhibitors of IL-6 signal transduction. Impaired function of SOCS3 ...

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