Literature Search

Suk(K),Lee(WH),Zheng(LT) Histol Histopathol 2026-06-11

...SYK-BTK pathways-converge on key transcription factors such as NF-κB, AP-1, STAT1/3, and NFAT to shape glial inflammator...

Cho(S),Gabr(MT) Bioorg Med Chem Lett 2026-10-00

...SYK) signaling. Together, these findings support the presence of a previously unrecognized ectodomain interaction mode f...

Clark(JC),Martin(EM),Slater(A),Calebiro(D),K… Blood Vessel Thromb Hemost 2026-05-00

...Syk. The results show that, when expressed at low level, GPVI and CLEC-2 diffuse over the cell surface as monomers with ...

Senevirathne(SE),Kanagy(WK),Hemmila(CR),Gree… J Immunol 2026-03-17

...Syk, drives second-messenger generation, and induces downstream Erk and Akt signaling and proinflammatory responses in m...

Wang(H),Yang(YH),Tang(JJ),Wang(XL),Liu(XY),W… Nat Commun 2026-08-14

...Syk/CARD9 axis governing Il1b transcription is defined, the epigenetic regulatory mechanisms remain elusive. Here, we id...

Fan(W),Han(S),Wang(C),Gao(J) J Mol Neurosci 2026-08-29

...SYK, and TNFSF13B. Among them, RGL2 emerged as the leading candidate, with the strongest downstream support concentrated...

Supiyani(A),Manalu(W),Sutardi(LN),Subangkit(… Turk J Biol 2026-00-00

...SYK, MMP9, AKT1, and ICAM1. The NP analysis identified three major bioactive compounds in LFM-macamide, N-benzyloleamide...

Rosell(R),González-Cao(M),Olmo-González(D),H… Ann Transl Med 2026-08-31

...Syk) signaling contributes to microglial activation and immune-related neurotoxicity during anti-programmed death 1 (PD-...

Fujii(Y),Hashimoto(S),Komatsu(Y),Suzuki(R),H… Mol Biol Rep 2026-08-29

...Syk, an upstream signaling component, but inhibited the phosphorylation of ERK1/2, which modulates cytokine production. ...

Su(J),Huang(L),Oh(Y),Zhang(J),You(L),Kaskada… Food Sci Biotechnol 2026-08-00

...Syk kinases and inhibited downstream PI3K-AKT-IKK signaling. Molecular docking and cellular thermal shift assays support...