Literature Search

Rallis(KS) Cancer Diagn Progn 2025-00-00

...TSC1/TSC2 and activation of the mTOR pathway are central to pathogenesis, particularly in tuberous sclerosis complex-ass...

McCoy(C),Dusing(M),Jerow(LG),Winstel(GC),Zha… Front Mol Neurosci 2025-00-00

...TSC1 or TSC2 genes. These mutations prevent the TSC1/TSC2 protein complex from forming, resulting in hyperactivation of ...

Yue(X),Zhang(Y),Zhao(N),Lang(T),Chen(G),Xion… Cell Death Dis 2025-11-14

...Tsc1-/- cells, Tsc1+/- and Tsc1c.2500-2503delAACA mice, as well as in Tsc2-/- cells, Tsc2+/- and Tsc2c.1113delA mice, wi...

Lane-Donovan(C),Paredes(M),Kao(AW) Prog Neurobiol 2025-12-00

...TSC1: tuberous sclerosis complex and frontotemporal dementia). We discuss why neurons seem particularly vulnerable to ly...

Xu(Zhi-Fang),Wang(Lin),Wang(Yang),Wang(Min),… Zhonghua Xue Ye Xue Za Zhi 2016-04-23

To investigate the effects of AML1B and AML1/ETO fusion gene on the transcription activity of TSC1 and TSC2 promotor and...

Guemann(Anne-Sophie),Andrieux(Joris),Petit(F… Cardiol Young 2016-01-08

...TSC1 molecular analysis, karyotype, and multiplex ligation probe amplification. TSC1 mutation was not found on foetal de...

Saxena(Anurag),Sampson(Julian R) Semin Neurol 2016-02-25

...TSC1 and TSC2 genes that cause tuberous sclerosis lead to hyperactivation of signaling via the mammalian target of rapam...

Tran(Lily H),Zupanc(Mary L) Pediatr Neurol 2016-03-28

Tuberous sclerosis complex is a genetic disease usually caused by mutations to either TSC1 or TSC2, where its gene produ...

Xu(Geyang),Li(Ziru),Ding(Li),Tang(Hong),Guo(… Diabetologia 2016-04-13

...Tsc1(-/-) mice, and STC-1 cells. GLP-1 expression was investigated by real-time PCR and western blotting. Plasma GLP-1 a...

Tresoldi(Silvia),Munari(Alice),Di Leo(Giovan… Radiology 2016-01-26

...TSC1 mutation, 65% (11 of 17) of patients with TSC2 mutation, and 12% (one of eight) of patients with TSC but without an...