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The granulocyte receptor carcinoembryonic antigen-related cell adhesion molecul…

Schmitter(Tim),Pils(Stefan),Sakk(Vadim),Fran… J Immunol 2007-05-22

...Vav2-deficient cells, CEACAM3-mediated internalization was only observed after re-expression of Vav. Vav colocalized wit...

Nek3 kinase regulates prolactin-mediated cytoskeletal reorganization and motili…

Miller(S L),Antico(G),Raghunath(P N),Tomasze… Oncogene 2007-08-16

...Vav2 becomes phosphorylated and activated, an event regulated by the serine/threonine kinase Nek3. Given the regulatory ...

Synergistic activation of PKD by the B cell antigen receptor and CD19 requires …

Vigorito(Elena),Kovesdi(Dorottya),Turner(Mar… Cell Signal 2007-04-05

...Vav2 dependent in response to BCR cross-linking, PKD activation is sensitive to the lack of Vav1 under synergistic stimu...

Vav proteins control MyD88-dependent oxidative burst.

Miletic(Ana V),Graham(Daniel B),Montgrain(Vi… Blood 2007-05-23

...Vav2, and Vav3. Vav proteins are also required for p38 MAPK activation and for normal regulation of proinflammatory cyto...

HER2/Neu (ErbB2) signaling to Rac1-Pak1 is temporally and spatially modulated b…

Wang(Shizhen Emily),Shin(Incheol),Wu(Frederi… Cancer Res 2007-11-06

...Vav2, activated Rac1, and Pak1 at cell protrusions. This results in prolonged Rac1 activation, enhanced motility and inv...

Loss of Vav2 proto-oncogene causes tachycardia and cardiovascular disease in mi…

Sauzeau(Vincent),Jerkic(Mirjana),López-Novoa… Mol Biol Cell 2007-04-24

...Vav2, and Vav3) are essential for proper signaling responses in hematopoietic cells. However, Vav2 and Vav3 are also hig...

Persistent activation of Rac1 in squamous carcinomas of the head and neck: evid…

Patel(Vyomesh),Rosenfeldt(Hans M),Lyons(Ruth… Carcinogenesis 2007-08-07

...Vav2 and an EGFR/Vav2-independent pathway that arises as a consequence of the oncogenic mutation of the H-ras proto-onco...

Activation of Vav/Rho GTPase signaling by CXCL12 controls membrane-type matrix …

Bartolomé(Rubén A),Molina-Ortiz(Isabel),Sama… Cancer Res 2006-02-23

...Vav2, which are activated by CXCL12 involving Jak activity. Blocking Vav expression by RNA interference results in impai...

Essential role of Vav family guanine nucleotide exchange factors in EphA recept…

Hunter(Sonja G),Zhuang(Guanglei),Brantley-Si… Mol Cell Biol 2006-08-09

...Vav2 and Vav3 as guanine nucleotide exchange factors (GEFs) that link the EphA2 receptor to Rho family GTPase activation...

VEGF controls endothelial-cell permeability by promoting the beta-arrestin-depe…

Gavard(Julie),Gutkind(J Silvio) Nat Cell Biol 2006-12-12

...Vav2, a guanine nucleotide-exchange factor. Rac activation, in turn, promotes the p21-activated kinase (PAK)-mediated ph...

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