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Vanadate enhances leptin-induced activation of JAK/STAT pathway in CHO cells.

Kita(Atsushi),Uotani(Shigeo),Kuwahara(Hiro... Biochem Biophys Res Commun 2003-05-13

...SOCS3 gene was also seen in vanadate-treated cell. Furthermore, vanadate reversed the inhibitory effects of SOCS3 on lep...

SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant ...

Takahashi(Yutaka),Carpino(Nick),Cross(Jame... EMBO J 2003-03-26

...SOCS3) binds cytokine receptors and thereby suppresses cytokine signaling. Deletion of SOCS3 causes an embryonic lethali...

IFN-alpha antagonistic activity of HCV core protein involves induction of sup...

Bode(Johannes G),Ludwig(Stephan),Ehrhardt(... FASEB J 2003-04-01

...SOCS3-mRNA expression, suggesting that the HCV core protein impairs IFN-alpha-induced signal transduction via induction ...

Growth impairment in IL-6-overexpressing transgenic mice is associated with i...

Lieskovska(Jaroslava),Guo(Donglin),Derman(... Growth Horm IGF Res 2003-08-29

...SOCS3, and CIS genes. We found a large, 5-fold increase in SOCS3 mRNA in the liver, brain, skeletal muscle, and the lung...

Leishmania donovani-induced expression of suppressor of cytokine signaling 3 ...

Bertholet(Sylvie),Dickensheets(Harold L),S... Infect Immun 2003-05-12

...SOCS3 mRNA was induced transiently after exposure to live or heat-killed parasites, but not purified lipophosphoglycan, ...

Alterations in Janus kinase (JAK)-signal transducers and activators of transc...

Podewski(Edith K),Hilfiker-Kleiner(Denise)... Circulation 2003-02-28

...SOCS3: -49%, P<0.01). Tyrosine-phosphorylation status of gp130 was increased (+60%, P<0.05), whereas tyrosine-phosphoryl...

A role of suppressor of cytokine signaling 3 (SOCS3/CIS3/SSI3) in CD28-mediat...

Matsumoto(Akira),Seki(Yoh-ichi),Watanabe(R... J Exp Med 2003-03-20

...SOCS3(+/-) mice enhanced CD28-mediated IL-2 production, clearly indicating the correlation between expression level of S...

Negative regulation of gp130 signalling mediated through tyrosine-757 is not ...

Fairlie(W Douglas),De Souza(David),Nicola(... Biochem J 2003-07-22

...SOCS3) and Src homology 2 domain-containing tyrosine phosphatase-2 (SHP2), are recruited to Y757 following receptor acti...

Suppressor of cytokine signaling 1 inhibits IL-10-mediated immune responses.

Ding(Yaozhong),Chen(Dongmei),Tarcsafalvi(A... J Immunol 2003-03-27

...SOCS3 expression and that forced constitutive expression of SOCS3 inhibits IL-10/STAT3 activation and LPS-induced macrop...

Adherence influences monocyte responsiveness to interleukin-10.

Petit-Bertron(Anne-France),Fitting(Catheri... J Leukoc Biol 2003-03-21

...SOCS3) expression were induced by IL-10 in both conditions, but a longer activation and/or expression were observed in a...

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