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Activation of signal transducer and activator transcription 3 and expression ...

Sakuda(Shigeru),Tamura(Shinji),Yamada(Akir... J Hepatol 2002-07-25

...SOCS3 mRNA were induced in regenerating liver after PH.,STAT3 signaling can occur in Kupffer cells and sinusoidal endoth...

Identification of suppressors of cytokine signaling (SOCS) proteins in human ...

Blumenstein(Marion),Bowen-Shauver(Jennifer... J Clin Endocrinol Metab 2002-04-08

...SOCS3 mRNA and protein, respectively, by human villous placenta, amnion and choriodecidua (n = 3-4). Tissues were obtain...

Cytokine signaling in the brain: putting a SOCS in it?

Wang(Jianping),Campbell(Iain L) J Neurosci Res 2002-03-20

...SOCS3 genes, can be highly regulated. Furthermore, roles for the SOCS are now evident in the modulation of neuroimmunoen...

The Stat1 binding motif of the interferon-gamma receptor is sufficient to med...

Woldman(I),Varinou(L),Ramsauer(K),Rapp(B),... J Biol Chem 2002-01-10

...SOCS3) inhibited the activation of Stat5 by the IFN-gamma receptor, and the Tyr-440-containing peptide stretch was suffi...

Interleukin-6-induced proliferation of pre-B cells mediated by receptor compl...

Friederichs(K),Schmitz(J),Weissenbach(M),H... Eur J Biochem 2002-01-15

...SOCS3 recruitment sites. Surprisingly, pre-B cells, after stimulation with low amounts of IL-6, proliferate much more ef...

The MKK6/p38 mitogen-activated protein kinase pathway is capable of inducing ...

Bode(J G),Ludwig(S),Freitas(C A),Schaper(F... Biol Chem 2002-05-23

...SOCS3 promoter. These data indicate that p38MAPK-activation is crucial for IL-6-induced SOCS3 expression and downregulat...

Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strate...

Shouda(T),Yoshida(T),Hanada(T),Wakioka(T),... J Clin Invest 2002-01-10

...SOCS3 is abundantly expressed in RA patients. To determine whether CIS3 is effective in treating experimental arthritis,...

Molecular regulation of urothelial renewal and host defenses during infection...

Mysorekar(Indira U),Mulvey(Matthew A),Hult... J Biol Chem 2002-04-01

...Socs3, Cebp/delta, Bcl3, and CC/CXC chemokines), induction of modulators of apoptotic responses (A20), and induction of ...

Listeria monocytogenes modulates macrophage cytokine responses through STAT s...

Stoiber(D),Stockinger(S),Steinlein(P),Kova... J Immunol 2001-02-08

...SOCS3) mRNA and protein. Contrasting our previous findings with LPS, maximal synthesis of SOCS3 required both the immedi...

Suppressor of cytokine signaling-3 is a biomechanical stress-inducible gene t...

Yasukawa(H),Hoshijima(M),Gu(Y),Nakamura(T)... J Clin Invest 2001-12-13

...SOCS3), an intrinsic inhibitor of JAK, shows biphasic induction in response to TAC. The induction of SOCS3 was closely c...

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