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Dysregulation of hepatic deiodinase type I in metabolically associated steato...

Lopez-Alcantara(N),Naujack(AM),Chen(Y),Tae... J Mol Endocrinol 2025-08-01

...Socs3 gene. In either model, DIO1 activity was increased, but neither thyroid hormone target genes nor metabolic paramet...

Transcriptional responses in different mouse models of septic liver injury di...

Yan(Q),Fan(W),He(X),Zheng(S),Zhong(X) Front Immunol 2025-00-00

...SOCS3 was validated as a potential SLI biomarker. Murine models partially replicate human SLI pathology but exhibit dist...

Translational Insights into Interferon Alpha's Effects on Immunomolecular Dyn...

García-Delgado(R),Luque-Lupiáñez(E),Mora-I... Cancers (Basel) 2025-07-08

...SOCS3, and TNFAIP3. Spearman correlations revealed functional associations between cytokine and gene expression patterns...

The Crosstalk Between Sepsis-Associated Encephalopathy and Alzheimer's Diseas...

Wang(Z),Zhang(Z),Shi(J),Zhao(R) Mol Neurobiol 2025-11-00

...SOCS3, CLEC4E, HSPB1, and HSPA1A. Pharmacological inhibition of the hub gene product C5aR1 using PMX205 improved cogniti...

Uncovering bifurcation behaviors of biochemical reaction systems from network...

Huang(YJ),Okada(T),Mochizuki(A) Sci Rep 2025-07-29

...SOCS3, which are experimentally testable.

Pro-inflammatory effects of endogenous and recombinant MDA-7/IL-24 with RGD p...

Daneshparvar(A),Hosseini(SY),Hamidizadeh(N... Sci Rep 2025-07-06

...SOCS3). Importantly, the RGD-modified variant exhibited the most pronounced effects, with PMDA-7-RGD inducing the highes...

Heightened Innate Immune and Inflammatory Gene Expression in the Skin of Seve...

Fernandes(IG),Ferreira(FM),De Sousa(ESA),P... J Inflamm Res 2025-00-00

...SOCS3 and NFKBIA indicate the involvement of anti-inflammatory mechanisms in the skin. Furthermore, deconvolution data i...

Elevating Jak-STAT signaling via SOCS3 deletion sustains photoreceptor viabil...

Wang(Y),Nusinowitz(S),Yang(XJ) Res Sq 2025-07-11

...SOCS3), which acts as a feedback inhibitor to dampen cytokine signaling. In this study, we investigated whether eliminat...

Genetic lesions in nodular lymphocyte-predominant Hodgkin lymphoma and T cell...

Rausch(T),Schäfer(H),Bein(J),Mölder(F),Bee... Leukemia 2025-09-00

...SOCS3, JUNB, IRF1 and ITPKB, were not the typical targets known from classical Hodgkin lymphoma (cHL). Two cases showed ...

GPR55 activation alleviates cognitive dysfunction caused by neuropathic pain ...

Zhao(F),Zhang(X),Liu(T),Sun(J),Li(X),Zhang... Cell Signal 2025-11-00

...SOCS3 signaling axis, as confirmed by pathway blockade using the specific inhibitor Compound C. These results demonstrat...

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