Zhu(Kun),Lei(Pin-Ji),Ju(Lin-Gao),Wang(Xiang)… Nucleic Acids Res 0000-00-00

...SPOP, a key subunit of the CUL3 ubiquitin E3 ligase complex, as a SETD2-interacting protein. We demonstrate that SPOP is...

Guo(Zhong-Qiang),Zheng(Tong),Chen(Baoen),Luo… Cancer Cell 0000-00-00

...SPOP-substrate protein interaction and can suppress oncogenic SPOP-signaling pathways. These inhibitors kill human ccRCC...

Zhao(Wencai),Zhou(Jiancheng),Deng(Zhuo),Gao(… Int J Oncol 0000-00-00

...SPOP in RCC have not been studied. In the present investigation, by assessing the immunohistochemical staining of SPOP i...

Cai(Hongchen),Liu(Aimin) Proc Natl Acad Sci U S A 0000-00-00

...Spop mutant skeletal defects. We further show that Spop directly targets the Gli3 repressor for ubiquitination and degra...

Hu(Xiaoyu),Yang(Zhu),Zeng(Manman),Liu(Y I),Y… Oncol Lett 0000-00-00

...SPOP gene, which was assessed by the appearance of monosomy 17 in the ovarian cancer samples; the deletion of the SPOP g...

Wu(Fei),Dai(Xiangpeng),Gan(Wenjian),Wan(Lixi… Cancer Lett 0000-00-00

...SPOP mutants failed to interact with Cdc20 to promote its degradation. As a result, SPOP-deficient prostate cancer cells...

Jung(Seung-Hyun),Kim(Min Sung),Jung(Chan Kwo… Oncotarget 0000-00-00

...SPOP, NF1, TCF12, IGF2BP3, KMT2C, CNOT1, BRIP1, KDM5C, STAG2 and MAP4K3) that have not been reported in thyroid follicul...