...TSC2 phosphorylation at S664, 1254 and 1798, and the antitumor activity by p38i. Remarkably, modulation of PP2AC level i...
...TSC2, tuberin), an event that is implicated in the induction of the mTOR pathway and subsequent tumorigenesis. High Mobi...
...TSC2(-/-) mouse embryonic fibroblasts, and identified IGFBP5 as a secreted, mTORC1 downstream effector protein. IGFBP5 i...
...TSC2 localization is not known. How TSC2 localization responds to combinations of stresses and other stimuli is also unk...
Tuberous sclerosis complex (TSC) disease results from inactivation of the TSC1 or TSC2 gene, and is characterized by ben...
...TSC2 phosphorylation and thus partially attenuates mTORC1 activity. This relieves feedback inhibition of upstream EGFR f...
...TSC2, the TSC1 and TSC2 gene products, form the TSC protein complex that senses specific cellular growth conditions to c...
...TSC2 (TSC, tuberous sclerosis complex) mutation in our patient. We speculate that a different pathway resulting in mTOR ...
...TSC2, cognitive level, sleep disorders, and other psychiatric problems, but not with seizure frequency, tubers localizat...
...TSC2 rs181088346 [odds ratio (OR) of each copy of variant allele = 0.77, 95% confidence interval (CI) = 0.65-0.88 for al...
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