Literature Search

Upadhyay(R),Orellana(A),Tsokos(GC),Bhargava(… Arthritis Rheumatol 2026-06-22

...SYK. MRL/lpr mice with nephritis exhibited elevated podocyte CLEC7A and SYK expression. Similarly, podocytes in kidney b...

Almansouri(D),Naasani(A),Zouboulis(CC) Expert Opin Pharmacother 2026-07-00

...SYK inhibitors (remibrutinib, fostamatinib), IRAK-4 inhibitors (zimlovisertib), and HSP-90 inhibitors (RGRN-305). Oral J...

Xia(Q),Hu(J),Sun(H),Zhu(Z),Jiang(W) TH Open None

...SYK), Bruton's tyrosine kinase (BTK), mitogen-activated protein kinase 1/2 (MEK1/2) and P38 but was enhanced by PLC and ...

Castillo(JC),Iglesias(E),Castillo(J),Fonte(L… J Fungi (Basel) 2026-06-14

...Syk-CARD9-NFκB, MAPK and STAT3 signalling pathways. This signalling promotes proinflammatory monocyte/macrophage polariz...

Zhang(G),Hu(C),Li(B),Qian(C),Zhang(H),Zhang(… Biomaterials 2026-12-00

...SYK) as a key upstream regulator whose aberrant activation drives neutrophil hyperactivation, neutrophil extracellular t...

Luo(H),Zeng(Q),Xie(N),Zhang(C),Liu(C),Chen(S… ACS Infect Dis 2026-07-10

...Syk) to the plasma membrane. Crucially, this Siglec-14/Syk axis functions as a necessary molecular scaffold that amplifi...

Moosavi(F),Hassani(B),Mortazavi(M),Peters(GJ… Cancers (Basel) 2026-06-16

...SYK. We have collected both computational studies and experimental reports, including functional assays, mechanistic stu...

Ahmad(S),Usman(M),Bibi(M),Aftab(MN),Aslam(MS) Int Immunopharmacol 2026-09-15

...Syk-CARD9, NF-κB and inflammasome signaling. These pathways shape both pro-inflammatory Th17/IL-22 responses that reinfo...

Li(L),Yang(Q),Zhang(H),Qi(Y),Xie(Y),Ding(Z),… Int Immunopharmacol 2026-09-15

...Syk-PI3K-Akt phosphorylation, accompanied by platelet hyperactivation. UDCA was associated with increased TREM2 expressi...

Cirinciani(M),Germelli(L),Da Pozzo(E),Priami… Sci Rep 2026-06-06

...Syk pathway, was assessed in two different human microglial in vitro models to verify its potential beneficial effects. ...