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Novel association of Vav2 and Nek3 modulates signaling through the human prolac…

Miller(Sommer L),DeMaria(Jamie E),Freier(Dav… Mol Endocrinol 2005-08-31

...Vav2/Nek3 with the PRL receptor. Increased Nek3 levels up-regulated Vav2 serine and tyrosine phosphorylation, whereas kn...

Vav2 as a Rac-GDP/GTP exchange factor responsible for the nectin-induced, c-Src…

Kawakatsu(Tomomi),Ogita(Hisakazu),Fukuhara(T… J Biol Chem 2005-04-05

...Vav2, a Rac-GEF. Nectins recruited and tyrosine-phosphorylated Vav2 through c-Src at the nectin-based cell-cell contact ...

The proto-oncogene Fgr regulates cell migration and this requires its plasma me…

Continolo(Silvia),Baruzzi(Anna),Majeed(Meyth… Exp Cell Res 2005-01-11

...Vav2, and bound to a protein complex formed by the Rho inhibitor p190RhoGAP and FAK, increasing p190RhoGAP phosphorylati...

Vav1 and vav3 have critical but redundant roles in mediating platelet activatio…

Pearce(Andrew C),Senis(Yotis A),Billadeau(Da… J Biol Chem 2005-03-14

...Vav2, and Vav3 play a crucial role in the regulation of phospholipase C gamma (PLC gamma) isoforms by immuno-tyrosine-ba...

Vav1/2/3-null mice define an essential role for Vav family proteins in lymphocy…

Fujikawa(Keiko),Miletic(Ana V),Alt(Frederick… J Exp Med 2004-01-15

...Vav2 and Vav3, with the first demonstration that Vav3 plays a critical compensatory function in T cells. Together, we de...

Epidermal growth factor-dependent regulation of Cdc42 is mediated by the Src ty…

Tu(Shine),Wu(Wen Jin),Wang(Jiabin),Cerione(R… J Biol Chem 2004-03-10

...Vav2, and overexpression of Vav2 together with activated Src (Src(Y529F)) can completely bypass the need for EGF to prom...

F-actin-dependent translocation of the Rap1 GDP/GTP exchange factor RasGRP2.

Caloca(Mariía J),Zugaza(José L),Vicente-Manz… J Biol Chem 2004-06-15

...Vav2, Dbl, and Rac1 leads to the shift of RasGRP2 from the cytosol to membrane ruffles and its co-localization with F-ac...

Vav proteins, masters of the world of cytoskeleton organization.

Hornstein(Idit),Alcover(Andres),Katzav(Shula… Cell Signal 2004-10-27

...Vav2 and Vav3 are more ubiquitously expressed. Vav proteins contain multiple domains that enable their function in vario...

RACK1 regulates G1/S progression by suppressing Src kinase activity.

Mamidipudi(Vidya),Zhang(Jian),Lee(Kelly C),C… Mol Cell Biol 2004-08-16

...Vav2, Rho GTPases, Stat3, and Myc. Consequently, cyclin D1 and cyclin-dependent kinases 4 and 2 (CDK4 and CDK2, respecti...

Neurotrophins regulate Schwann cell migration by activating divergent signaling…

Yamauchi(Junji),Chan(Jonah R),Shooter(Eric M) Proc Natl Acad Sci U S A 2004-08-17

...Vav2 and RhoA. Together, these results suggest that neurotrophins and their receptors differentially regulate Schwann ce...

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