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Analysis of STAT1 expression and biological activity reveals interferon-tau-d...

Vitorino Carvalho(A),Eozenou(C),Healey(G D... Reprod Fertil Dev 0000-00-00

...SOCS3) gene promoters consistent with the induction of their transcripts. Our data provide novel molecular insights into...

Saikosaponin d protects against acetaminophen-induced hepatotoxicity by inhib...

Liu(Aiming),Tanaka(Naoki),Sun(Lu),Guo(Bin)... Chem Biol Interact 0000-00-00

...Socs3, Fga, Fgb and Fgg. SSd also enhanced the expression of the anti-inflammatory cytokine Il10 mRNA. Collectively, the...

Biochemical and functional analyses of gp130 mutants unveil JAK1 as a novel t...

Poussin(Karine),Pilati(Camilla),Couchy(Gab... Oncoimmunology 0000-00-00

...SOCS3), a physiological gp130 inhibitor. Specifically, cells expressing a double mutant variant of gp130 with a disrupte...

Xinqin exhibits the anti-allergic effect through the JAK2/STAT5 signaling pat...

Zhang(Qian),Xiong(Ying),Li(Guo-Bing),Tang(... J Ethnopharmacol 0000-00-00

...SOCS3) were evaluated by Western blot.,Treatment with Xinqin resulted in AR symptoms and decreases in levels of histamin...

[Methylation Status of the SOCS3 Gene Promoter in H2228 Cells and 
EML4-ALK-p...

Liu(Chunlai),Li(Yongwen),Dong(Yunlong),Zha... Zhongguo Fei Ai Za Zhi 0000-00-00

...SOCS3 promoter in EML4-ALK-positive H2228 cells and lung cancer tissues.,The methylation status of the SOCS3 promoter in...

MicroRNA-19a-3p enhances the proliferation and insulin secretion, while it in...

Li(Yuan),Luo(Tianyou),Wang(Liang),Wu(Jing)... Int J Mol Med 0000-00-00

...SOCS3 acts as a downstream effector in the miR-19a-3p-mediated function of pancreatic β cells. Finally, the level of SOC...

Crosstalk between different family members: IL27 recapitulates IFNγ responses...

Rolvering(Catherine),Zimmer(Andreas D),Koz... Biochim Biophys Acta 0000-00-00

...SOCS3-mediated mechanism. Thus, IL27 recapitulates IFNγ responses in liver cells, but differs from IFNγ by its sensitivi...

AAV-mediated IL-10 gene transfer counteracts inflammation in the hypothalamic...

Nakata(Masanori),Yamamoto(Sawako),Okada(Ta... Neuropeptides 0000-00-00

...SOCS3 expression in ARC. Overexpression of mIL-10 using AAV vector ameliorated obesity in parallel with restoration of A...

Curcumin Suppressed Activation of Dendritic Cells via JAK/STAT/SOCS Signal in...

Zhao(Hai-Mei),Xu(Rong),Huang(Xiao-Ying),Ch... Front Pharmacol 0000-00-00

...SOCS3, and PIAS3) from this pathway were highly expressed. In conclusion, curcumin suppressed the activation of DCs by m...

M2A and M2C Macrophage Subsets Ameliorate Inflammation and Fibroproliferation...

Tang(Lunxian),Zhang(Hua),Wang(Chunmei),Li(... Shock 0000-00-00

...SOCS3 signaling pathway. After blocking IL-10, these superior effects of M2c over M2a were abolished. These data imply t...

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