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Pancreatic neuroendocrine tumor in a child with a tuberous sclerosis complex 2 …

Bombardieri(Roberta),Moavero(Romina),Roberto… Endocr Pract 2014-06-12

...TSC2 mutation presented with a nonsecretory PanNET discovered during routine annual abdominal ultrasound. Surgical dista...

Phenytoin-associated severe hypocalcemia with seizures in a patient with a TSC2…

Nseir(Ghaleb),Golshayan(Dela),Barbey(Frédéri… Ren Fail 2014-03-03

...TSC2-PKD1 contiguous gene syndrome. This patient was under prophylactic treatment of phenytoin since 2 years because of ...

The ominous sequence in patients with tuberous sclerosis complex.

Yamada(Hiroshi),Akiyoshi(Kensuke),Izumi(Tats… Brain Dev 2014-11-04

...TSC2 gene mutations.,The sequence of progressively proliferative renal angiomyolipoma, facial angiofibroma, West syndrom...

Self-reported reproductive health in women with tuberous sclerosis complex.

Gabitzsch(Emily K),Hashmi(Syed S),Koenig(Mar… Genet Med 2014-07-14

...TSC2 genes cause tuberous sclerosis complex, and recent evidence points to a crucial role for these genes in maintaining...

Tuberous sclerosis.

Curatolo(P),Maria(B L) Handb Clin Neurol 2014-04-01

...TSC2, encoding hamartin and tuberin respectively. The hamartin-tuberin complex inhibits the mammalian-target-of-Rapamyci...

The acute effects of strength, endurance and concurrent exercises on the Akt/mT…

de Souza(E O),Tricoli(V),Bueno Junior(C),Per… Braz J Med Biol Res 2014-03-14

...TSC2 (p-TSC2) expression were evaluated by immunoblotting in total plantaris muscle extracts. The only significant diffe...

Loss of TSC2 confers resistance to ceramide and nutrient deprivation.

Guenther(G G),Liu(G),Ramirez(M U),McMonigle(… Oncogene 2014-05-27

...TSC2-deficient cells would be hypersensitive to ceramide. However, murine embryonic fibroblasts (MEFs) lacking TSC2 were...

Akt regulates glutamate receptor trafficking and postsynaptic membrane elaborat…

Lee(Hyun-Gwan),Zhao(Na),Campion(Bridget K),N… Dev Neurobiol 2014-04-11

...TSC2 complex, an inhibitor of TOR (Dimitroff et al., 2012). Therefore, we examined the role of Akt in the assembly and p...

Fisetin regulates obesity by targeting mTORC1 signaling.

Jung(Chang Hwa),Kim(Heemun),Ahn(Jiyun),Jeon(… J Nutr Biochem 2014-02-06

...TSC2-knockdown cells. The results suggested that fisetin treatment inhibits mTORC1 activity in an Akt-dependent manner. ...

A circuitry and biochemical basis for tuberous sclerosis symptoms: from epileps…

Feliciano(David M),Lin(Tiffany V),Hartman(Na… Int J Dev Neurosci 2014-06-27

...TSC2, resulting in increased activity of the mammalian Target of Rapamycin (mTOR). Here, we explore the cytoarchitectura...

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