...TSC2(-/-) ASM cells, derived from a human renal angiomyolipoma, require epidermal growth factor (EGF) for proliferation....
...TSC2, whose protein products dimerize and negatively regulate mammalian target of rapamycin (mTOR) signalling. TSC is an...
...tsc2ang1 cells derived from a skin tumor from a mouse heterozygous for tsc2. Treatment of tsc2ang1 cells with a combinat...
...TSC2/AMPK-mediated mTOR inhibition but not on beclin-1. Inhibition of autophagy prevented GRP78-mediated endocrine resis...
...TSC2 and mTOR.,An ischemic microenvironment leads to a reduction in PI3K activity with subsequent induction of apoptosis...
...TSC2 to inactivate Rheb, thereby inhibiting signaling by the mammalian target of rapamycin (mTOR) complex 1 (mTORC1). mT...
...TSC2 proteins was closely correlated with the enhanced viral replication in drs-KO MEFs. Drs protein could associate wit...
...Tsc2. Neurogenesis persists postnatally in the human subventricular zone (SVZ) where slow-growing tumors containing Tsc-...
...Tsc2 gene underlies TSC pathogenesis, but involvement of specific neural cell populations in the formation of TSC-associ...
...TSC2) and GERD, 2 SNPs (rs2295778 of HIF1AN, rs2296188 of VEGFR1) and smoking, and 7 SNPs (rs2114039 of PDGRFA, rs229618...
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