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Acetoacetyl-CoA synthetase modulates lipid partitioning and cholesterol-relat...

Tian(Y),Wang(S),Loor(JJ),Fan(W),Chang(Y),Y... J Steroid Biochem Mol Biol 2026-09-00

...ACAT2) was downregulated. NEFA challenge also reduced BDH1 and CPT1A levels, decreased intracellular total cholesterol, ...

Systems pharmacology approaches to modeling immune training and tolerance.

Kırboğa(KK),Rudrapal(M) Curr Opin Pharmacol 2026-08-00

...ACAT2. ML algorithms integrated with explainable AI frameworks have facilitated biomarker discovery and therapeutic targ...

Integrated Analysis of Transcriptome and Metabolome Reveals Molecular Respons...

Zhao(Y),Ding(Y),Zhou(F),Hu(X),Yang(Q),Cao(... Biology (Basel) 2026-04-13

...ACAT2)), autophagy (e.g., autophagy-related protein 101-like (atg101)), immune regulation pathway (e.g., V-type proton A...

Cell type-specific alterations in fatty acid metabolism in neuronal subpopula...

Zhao(C),Zhang(L),Yang(P),Li(L),Zeng(W),Xie(W) Front Psychiatry None

...ACAT2, ACSS1, PSME1, and S100A10). Subsequent analysis indicated that these genes not only participate in inflammatory r...

Proteomic Profiling Reveals the Synergistic Effects of Astaxanthin and Melato...

Li(C),Zhang(Y),Ni(X),Zhao(X),Liang(J),Wu(G... J Proteome Res 2026-06-05

...ACAT2, PRDX6, G6PD, HSP90a, HSPA8, HSL, ACTN1, and Ezrin, and negative proteins like Cyt c, CTSF, and AFU, which are tig...

Effects of dietary taurine supplementation on polyunsaturated fatty acids, ch...

Wang(S),Zhang(Q),Lu(H),Yu(M),Alagawany(MM)... Front Nutr None

...ACAT2 mRNA expression (p < 0.05); 0.2% taurine promoted hepatic bile acid synthesis rate-limiting enzyme CYP7A1 mRNA exp...

Is acyl-CoA cholesterol acyltransferase 2 the enzyme responsible for the este...

Blanco(J),Martín(H),Martín-Gómez(L) Aquat Toxicol 2026-06-00

...ACAT2) is the main enzyme responsible for OA esterification. Mammal ACAT2 inhibitors reduced OA esterification in mussel...

Acetyl coenzyme A acetyltransferase 2 is a novel regulator of liver regenerat...

Zhou(J),Bao(Z),Wu(M),Gong(S),Miao(X),Dong(... Life Sci 2026-06-15

...Acat2 expression whereas ChIP assay detected direct binding of GATA4 to the Acat2 promoter. Supplementation with a wild ...

Intestinal microbiota-host crosstalk reveals mechanisms regulating residual f...

He(Z),Chi(X),Ruan(S),Lin(R),Chen(H),Cai(K)... BMC Genomics 2026-04-21

...ACAT2, LSS, FDFT1, SQLE, IDI1, CYP51A1) were significantly correlated with the abundance of key genera. CONCLUSIONS: Pae...

Phytosterol alleviates cholesterol accumulation by influencing intestinal est...

Zhao(T),Zhang(Y),Wang(Z),Yin(J),Nie(S),Jia... J Adv Res 2026-03-22

...ACAT2 active site, selectively enhancing PS turnover. This asymmetric compensatory mechanism redirected ACAT2 substrate ...

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